Table 4.
Logistic regression analysis for the association of 6 protein biomarkers with type 1 diabetes in combined first- and second-group data
| Controls vs T1D, OR | P | T2D vs T1D, OR | P | |
|---|---|---|---|---|
| OPN | 0.039 (0.006-0.284) | .001 | 0.201 (0.088-0.462) | 1.567E-4 |
| IL-1RA | 37.314 (9.886-140.840) | 9.264E-8 | 8.022 (3.822-16.838) | 3.713E-8 |
| YKL-40 | 37.820 (4.691-304.888) | 6.457E-4 | 0.443 (0.164-1.199) | .11 |
| M-CSF | 21.325 (2.969-153.157) | .002 | 0.697 (0.100-1.879) | .13 |
| TRAIL | 0.003 (0.000-0.032) | 2.03E-6 | 0.778 (0.175-3.453) | .74 |
| SAA | 0.969 (0.499-1.881) | .93 | 1.308 (0.924-1.850) | .13 |
Age and sex were included as covariates in a logistic regression; OR (odds ratio) and 95% CI are presented.
Abbreviations: IL-1RA, interleukin 1 receptor antagonist; M-CSF, macrophage colony-stimulating factor 1; OPN, osteopontin; SAA, serum amyloid A1T1D, type 1 diabetes; T2D, type 2 diabetes; TRAIL, tumor necrosis factor superfamily member 10; YKL-40, chitinase 3-like 1.