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. 2022 Aug 11;2022:5411462. doi: 10.1155/2022/5411462

Figure 2.

Figure 2

Schisandrin A reduced acute kidney injury in mice of DN. (a) E-cadherin mRNA expression; (b) periostin mRNA expression in mice of DN; (c) E-cadherin mRNA expression, (d) periostin mRNA expression in vitro model of DN; (e) PAS staining; (f) TUNEL staining and (g) collagen IV staining in mice of DN; and (h) podocyte ultrastructure changes using electron microscope in mice of DN. Control, sham control mice group; model, STZ-induced mice DN group; low, mice DN by treatment with 25 mg/kg of Schisandrin A group; med, mice DN by treatment with 50 mg/kg of Schisandrin A group; high, mice DN by treatment with 100 mg/kg of Schisandrin A group; ##P < 0.01 versus control group; ∗∗P < 0.01 versus STZ-induced mice DN group.