Table 3.
Recommendations for perioperative use of oral and non-insulin injectable antidiabetic drugs.
| Class (trade name) | Previous day | Day of surgery |
|
|---|---|---|---|
| Morning surgery | Afternoon surgery | ||
| Biguanides | Regular use, unless contraindicateda | ||
| Metformin (Glifage®) | |||
| Sulphonylureas | Regular use | Omit the dose regardless of the time | |
| Gliclazide (Diamicron®) | |||
| Glibenclamide (Daonil®) | |||
| Glimepiride (Amaryl®) | |||
| Glipizide (Glucotrol®) | |||
| Glinides | Regular use | Omit the morning dose | Take the morning dose (pre-meal) if the patient had breakfast |
| Nateglinide (Starlix®) | |||
| Repaglinide (Prandin®) | |||
| Alpha-glucosidase inhibitors | |||
| Acarbose (Glucobay®) | |||
| Glitazones | Regular use | Regular use (attention to patients at risk for cardiac congestion) | |
| Rosiglitazone (Avandia®) | |||
| Pioglitazone (Actos®) | |||
| DPP-4 inhibitors | Regular use | Regular use2 or omit the dose on the day of surgery (potential delay of gastric emptying)8 | |
| Sitagliptin (Januvia®) | |||
| Vildagliptin (Galvus®) | |||
| Saxagliptin (Onglyza®) | |||
| Alogliptin (Nesina®) | |||
| Linagliptin (Trayenta®) | |||
| GLP1 analogs | |||
| Exenatide (Byetta® Bydureon®) | |||
| Liraglutide (Victoza®) | |||
| SGLT-2 inhibitors | Regular use | Omit dose on the day of surgery. Attention for concomitant use of diuretics. | |
| Dapaglifozina (Forxiga®) | |||
| Canaglifozina (Invokana®) | |||
| Empaglifozina (Jardiance®) | |||