Table 2.

Estimated odds of change in preoperative tests according to characteristics of interest over time and results of comparative tests.

	Months							pa
	12	24	36	48	60	72	84
All	1.9 (0.9–2.9)	6 (4.2–7.8)	9.4 (7–11.8)	15.4 (12.1–18.7)	22.4 (18.1–26.7)	34.5 (27.6–41.4)	62.4 (46.7–78.1)
Age								0.009
<50 years	1.7 (0.5–2.9)	3.6 (1.8–5.4)	6.4 (3.9–8.9)	13.6 (9.3–17.9)	20.2 (14.5–25.9)	30.1 (21.5–38.7)	44 (29.1–58.9)
≥50 years	2.1 (0.7–3.5)	9.2 (5.9–12.5)	13.4 (9.3–17.5)	17.8 (12.7–22.9)	25.3 (18.4–32.2)	39.9 (29.1–50.7)	87.6 (66.8–100)
ASA								<0.001
I	2 (0.8–3.2)	5 (2.8–7.2)	7.4 (4.7–10.1)	13.6 (9.1–18.1)	18.7 (13–24.4)	26.8 (18.2–35.4)	38.6 (23.3–53.9)
II	1.4 (0.2–2.6)	5.4 (2.9–7.9)	10.1 (6.4–13.8)	16.1 (11.2–21)	22.1 (15.6–28.6)	37.3 (26.9–47.7)	73.8 (55–92.6)
III	5.5 (012.9)	22 (7.5–36.5)	25.4 (10.1–40.7)	29.5 (13–46)	56.9 (33.4–80.4)	71.3 (43.5–99.1)	71.3 (43.5–99.1)
Comorbidities								<0.001
No	2.1 (0.9–3.3)	4.1 (2.3–5.9)	6.3 (3.8–8.8)	12.1 (8–16.2)	16.3 (11.2–21.4)	23.1 (15.7–30.5)	33 (20.5–45.5)
Yes	1.6 (0.4–2.8)	8.3 (5.2–11.4)	13.2 (9.1–17.3)	19.5 (14.2–24.8)	29.7 (22.4–37)	48.2 (36.8–59.6)	83.6 (68.1–99.1)
Chemotherapy								0.001
No	1.6 (0.4–2.8)	3.5 (1.5–5.5)	6.5 (3.6–9.4)	12.8 (8.5–17.1)	17.2 (11.5–22.9)	30.7 (20.7–40.7)	41 (27.3–54.7)
Yes	2.2 (0.8–3.6)	8.4 (5.7–11.1)	12.3 (8.8–15.8)	17.8 (13.1–22.5)	27.6 (20.9–34.3)	38.4 (29–47.8)	80.1 (59.5–100)
Radiotherapy								0.012
No	1.7 (0.5–2.9)	3.8 (1.8–5.8)	6 (3.3–8.7)	11.3 (7.2–15.4)	17.3 (11.4–23.2)	29 (18.8–39.2)	76.7 (51.8–101.6)
Yes	2.1 (0.7–3.5)	8.1 (5.4–10.8)	12.8 (9.116.5)	19.4 (14.5–24.3)	27.1 (20.6–33.6)	39.4 (30.2–48.6)	50.4 (37.7–63.1)

Values presented as % (95% confidence interval).

^aLog-rank test.

ASA, American Society of Anesthesiologists Physical Status Classification.