Table 2.
Proportion of the association between TBDM and associated risk factors, Brazil, 2007-2014.
| Variables | <12 years |
12-17 years |
18-59 years |
60 years or more |
||||
|---|---|---|---|---|---|---|---|---|
| n/% | OR (95% CI) | n/% | OR (95% CI) | n/% | OR (95% CI) | n/% | OR (95% CI) | |
| Sex | ||||||||
| Male | 112/1.4 | 1.00 | 101/0.9 | 1.00 | 18,238/5.7 | 1.00 | 8167/15.1 | 1.00 |
| Female | 63/1.0 | 0.67 (0.49-0.92) | 117/1.1 | 1.19 (0.91-1.55) | 9813/6.5 | 1.15 (1.12-1.18) | 5689/20.1 | 1.41 (1.36-1.47) |
| Race/skin color | ||||||||
| Caucasian | 61/1.4 | 1.00 | 95/1.4 | 1.00 | 9535/5.7 | 1.00 | 5568/16.9 | 1.00 |
| Black and brown | 85/1.1 | 0.79 (0.57-1.11) | 90/0.7 | 0.5 (0.37-0.66) | 15,297/5.6 | 0.98 (0.96-1.01) | 6800/17.0 | 1.01 (0.97-1.05) |
| Asian and indigenous | 7/0.8 | 0.57 (0.26-1.25) | 5/0.8 | 0.56 (0.22-1.37) | 447/5.4 | 0.93 (0.84-1.03) | 219/11.0 | 0.61 (0.53-0.70) |
| Clinical form | ||||||||
| Pulmonary | 155/1.5 | 1.00 | 200/1.1 | 1.00 | 25,934/6.0 | 1.00 | 12,334/17.4 | 1.00 |
| Extra-pulmonary | 20/0.5 | 0.37 (0.23-0.59) | 18/0.5 | 0.47 (0.29-0.76) | 2119/3.1 | 0.50 (0.48-0.53) | 1524/13.7 | 0.76 (0.72-0.80) |
| Type of admission | ||||||||
| New Case | 147/1.1 | 1.00 | 189/0.9 | 1.00 | 23,628/5.8 | 1.00 | 12,160/17.2 | 1.00 |
| Recurrence | 10/3.4 | 3.06 (1.59-5.87) | 9/1.9 | 2.05 (1.04-4.02) | 1880/5.5 | 0.95 (0.90-0.99) | 834/14 | 0.79 (0.73-0.85) |
| Readmission after default | 4/1.3 | 1.14 (0.42-3.11) | 4/0.6 | 0.67 (0.25-1.81) | 1214/3.4 | 0.57 (0.53-0.60) | 263/13.2 | 0.73 (0.64-0.83) |
| Transfer | 13/1.9 | 1.67 (0.94-2.95) | 15/1.8 | 1.93 (1.13-3.27) | 1256/6.4 | 1.11 (1.05-1.18) | 548/17.9 | 1.05 (0.95-1.15) |
| Education | ||||||||
| Illiterate | 1/0.8 | 1.00 | 3/1.3 | 1.00 | 1235/7.1 | 1.00 | 1594/13.7 | 1.00 |
| Less than 9 years of education | 13/0.4 | 0.5 (0.06-3.84) | 134/0.9 | 0.67 (0.21-2.12) | 16,501/5.7 | 0.79 (0.74-0.84) | 7131/17.7 | 1.35 (1.27-1.43) |
| 9 years or more | 0/0 | – | 2/0.9 | 0.73 (0.12-4.39) | 1234/4.8 | 0.66 (0.60-0.71) | 525/18.9 | 1.46 (1.31-1.61) |
| Outcome | ||||||||
| Cure | 124/1.2 | 1.00 | 155/0.9 | 1.00 | 20,178/5.9 | 1.00 | 9232/17.3 | 1.00 |
| Treatment default | 3/0.3 | 0.29 (0.09-0.91) | 15/0.7 | 0.84 (0.50-1.44) | 2236/3.4 | 0.56 (0.54-0.59) | 633/14.4 | 0.80 (0.73-0.87) |
| Death | 13/2.3 | 1.99 (1.12-3.54) | 14/3.9 | 4.53 (2.60-7.92) | 1066/8.0 | 1.15 (1.10-1.20) | 2112/15.8 | 0.89 (0.85-0.94) |
| Transfer | 20/1.6 | 1.4 (0.87-2.26) | 27/2.0 | 2.26 (1.49-3.41) | 2089/6.7 | 1.02 (0.97-1.06) | 899/18.5 | 1.08 (1.00-1.16) |
| MDR-TB | 1/4.3 | 3.83 (0.51-8.65) | 2/2.1 | 2.37 (0.58-9.71) | 290/9.1 | 1.6 (1.41-1.80) | 88/27.4 | 1.8 (1.41-2.31) |
| Regimen change | 0/0.0 | – | 0/0.0 | – | 18/8.5 | 1.49 (0.92-2.42) | 10/20.0 | 1.19 (0.60-2.38) |
| Failure | 0/0.0 | – | 0/0.0 | – | 7/11.7 | 2.11 (0.96-4.65) | 1/8.3 | 0.43 (0.06-3.36) |
| Follow-up sputum smear | ||||||||
| 2nd month | ||||||||
| Positive | 9/5.1 | 1.00 | 13/1.7 | 1.00 | 2056/7.6 | 1.00 | 827/20.5 | 1.00 |
| Negative | 38/2.4 | 0.45 (0.21-0.95) | 59/0.9 | 0.52 (0.28-0.96) | 8128/5.9 | 0.76 (0.72-0.80) | 3688/17.0 | 0.8 (0.73-0.87) |
| Not performed | 73/0.9 | 0.16 (0.08-0.32) | 98/0.9 | 0.54 (0.30-0.96) | 11,236/5.3 | 0.67 (0.64-0.71) | 5619/16.6 | 0.77 (0.71-0.84) |
| 6th month | ||||||||
| Positive | 0/0.0 | 1.00 | 3/4.8 | 1.00 | 239/7.7 | 1.00 | 105/19.9 | 1.00 |
| Negative | 55/3.3 | 4.75 (3.26-6.92) | 57/0.9 | 0.18 (0.05-0.60) | 8321/6.2 | 0.79 (0.69-0.90) | 3803/16.9 | 0.82 (0.66-1.01) |
| Not performed | 56/0.7 | – | 94/1.0 | 0.19 (0.06-0.62) | 10,556/5.5 | 0.69 (0.61-0.79) | 5085/17.1 | 0.83 (0.67-1.03) |
Source: National disease notification system (Sistema de Informação de Agravos de Notificação – SINAN). Note: *logistic regression model.