Table 3.
Doubling times (Dt) of Histoplasma capsulatum yeasts at 37 and 40 °C.
| Isolate/Strain | Dt (h)a |
Changes of Dt from 37 to 40°C | |
|---|---|---|---|
| 37°C | 40°C | ||
| EH-316 | 4.36 | 5.00 | Increase |
| EH-317 | 5.12 | 6.00 | Increase |
| EH-319 | 1.36 | 1.54 | Increase |
| EH-323 | 4.06 | 5.18 | Increase |
| EH-324 | 4.30 | 4.36 | Increase |
| EH-325 | 5.00 | 6.24 | Increase |
| EH-326 | 3.18 | 3.18 | NC |
| EH-328 | 4.42 | 4.48 | Increase |
| EH-355 | 4.24 | 5.36 | Increase |
| EH-356 | 5.12 | 4.48 | Decrease |
| EH-359 | 6.54 | 8.54 | Increase |
| DMic993444 | 6.06 | 6.42 | Increase |
| DMic993445 | 5.18 | 4.54 | Decrease |
| DMic993446 | 6.36 | 7.24 | Increase |
| DMic993267 | 5.36 | 7.36 | Increase |
| DMic01739 | 6.42 | 9.42 | Increase |
| LA | 5.18 | 4.42 | Decrease |
| AP | 4.24 | 3.18 | Decrease |
| WE | 5.42 | 4.24 | Decrease |
| MZ 2 | 8.30 | 7.42 | Decrease |
| GeM | 5.00 | 7.06 | Increase |
| H.1.02.W | 7.24 | 8.00 | Increase |
| G-186B | 5.42 | 5.48 | Increase |
| G-217B | 3.30 | 4.24 | Increase |
| Downs | 7.36 | NA | NA |
| Meansb | 5.14 ± 1.47 | 5.55 ± 1.87 | |
NC, No changes; NA, Not applicable.
a
Dt estimation was performed according to the equation described in the Material and Methods section.
b
Data at 37 and 40 °C are presented as the means of H. capsulatum yeast Dt values ± SD, on the basis of three independent assays, using n = 12 per OD value.