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. 2020 Apr 21;24(3):231–238. doi: 10.1016/j.bjid.2020.03.002

Table 1.

Summary of mobile genetic elements reported in carbapenemase-producing Enterobacterales in South America.

Country Isolate Replicon typing (incompatibility group) Transposable element Carbapenemase gene Reference
Argentina K. pneumoniae ST258 L/M Tn4401a blaKPC-2 8
C. freundii, E. cloacae
K. pneumoniae non-258
HI2, L/M, A/C NTE: variant Ia and Variant Ib blaKPC-2 8
P. rettgeri
E. coli
B/O Tn125
Class 1 integron
blaNDM-1
blaIMP-8
9, 10
E. cloacae Non-typeable Class 1 integron: In883, In885, In346 and In900 blaVIM-2 and blaVIM-11 11
K. pneumoniae N/D IS4321-IS4 blaOXA-48 13
Colombia K. pneumoniae ST14 ST 387, ST388 L/M Tn4401b blaKPC-2 16, 17
K. pneumoniae ST258 N/D Tn4401a or Tn4401b blaKPC-2
blaKPC-3
16
K. pneumoniae ST147 and ST14 N/D Tn4401a or Tn4401b blaKPC-2 18
K. pneumoniae ST512 N/D Tn4401b blaKPC-3 17
S. marcescens A/C Tn4401b blaKPC-2 18
E. coli F Tn4401b blaKPC-2 18
E. coli A/C Tn125 and Tn5393 blaNDM-1 19
K. pneumoniae ST1043 A/C N/D blaNDM-1 20
Brazil K. pneumoniae ST258, ST11 and ST48 FII Tn4401a blaKPC-2 21
K. pneumoniae ST327 and ST437 and E. coli
K. pneumoniae
N
Q1
Tn4401b
NTE
blaKPC-2
blaKPC-2
21, 23
S. marcescens and C. freundii L/M N/D blaKPC-2 25
E. coli, E. cloacae, E. aerogenes, C. freundii and P. stuartii N/D Tn4401b and Tn4401d blaKPC-2 25
K. pneumoniae ST11 and E. coli ST502
K. pneumoniae ST1781
W
IncQ
Tn4401c
ISKpn23
blaKPC-2
blaBKC-1
21, 26
Enterobacter hormaechei FII ISAba125 and Tn3000 blaNDM-1 27, 29
P. rettgeri
E. coli
N/D
IncX3
Tn125
Tn3000
blaNDM-1
blaNDM-1
28, 29
K. pneumoniae, P. rettgeri
S. marcescens
N/D
N/D
Class I integrons
Class I integrons
blaIMP-1
blaIMP-10
30, 32
E. hormaechei N/D Tn3 truncated-Tn4 truncated blaOXA-370 33
Chile K. pneumoniae ST258, ST101, ST25 N/D Tn4401a blaKPC-2 36
K. pneumoniae ST258, ST101, ST25 N/D NTE: variant 1a blaKPC-2 36
Ecuador K. pneumoniae ST147
K. pneumoniae ST248, 25, 42
Raoultella ornithinolytica
A/C
FII
N/D
N/D
Tn4401a
Tn1999
blaNDM-1
blaKPC-2
blaOXA-48
34, 35
Uruguay K. pneumoniae ST 258 N/D Tn4401a blaKPC-2 37
Venezuela K. pneumoniae ST11, ST15, ST833, ST1271, ST1857, ST1859 and ST1860 N/D Tn4401b blaKPC-2 38
K. pneumoniae ST833 N/D class 1 integron blaVIM-2-blaKPC-2 39

N/D: not determined.