Table 3.
Carbapenem susceptibility trend analysis in Gram-negative bacteria recovered in HCAIs (2012–17).
| Gram-negative bacteria noted in HCAIs (all sites) | SAPC 2012–2017 | Joinpoint | 95% CI | p-Value |
|---|---|---|---|---|
| Carb-S% | ||||
| E. coli | −0.02 (2012–2017) | 0 | −0.24, 0.19 | 0.82 |
| K. pneumoniae | −10.71 (2012–2014) | 1 | −18.02, −2.75 | 0.02 |
| 6.54 (2015–2017) | −2.00, 15.83 | 0.12 | ||
| Enterobacter spp. | 0.53 (2012–2017) | 0 | −0.24, 1.30 | 0.16 |
| Other Enterobacterales | 9.60 (2012–2013) | 1 | 5.48, 13.88 | 0.00 |
| 0.08 (2013–2017) | −0.23, 0.39 | 0.57 | ||
| P. aeruginosa | 1.49 (2012–2017) | 0 | −0.17, 3.17 | 0.07 |
| A. baumannii | −2.49 (2012–2017) | 0 | −7.26, 2.52 | 0.29 |
HCAIs, healthcare-associated infections; SAPC, semiannual percent change by Joinpoint regression; CARB, carbapenem; CI, confidence interval; Carb-S, carbapenem-susceptible.