Table 1.

Patient demographics, presenting symptoms, clinical and peripheral nerves ultrasound characterization.

		Emergency room		Clinical characterization		Ultrasound of peripheral nerves
Patient No.	Age, y/ Sex	Reason for attendance / symptom duration	Diagnosis of referral	Skin	Nerves	No. of points asymmetric by thickening (>2 mm2 CSA R/L difference)	No. of focallity intranerve points detected (>2 mm2 difference)	No. of qualitative morphologically altered points	Intra / perineural Doppler signal
1	70/M	Tingling in the LUL / 2 years	ACS	Large anesthetic area on the left leg and foot; localized irregular patches of circumscribed hair loss on left lower limb	Enlargement of the left common fibular, left superficial fibular and right posterior tibial nerves; electric shock-like pain on the right superficial fibular and right posterior tibial nerves	5	2	5	Negative
2	64/F	Tingling in the LUL / 5 months	ACS	Anesthetic hypochromatic macule on the left elbow and forearm; localized irregular patches of circumscribed hair loss on lower limbs; incomplete endogenous histamine test	Enlargement and electric shock-like pain on the common fibular and left ulnar nerves	4	5	4	Positive
3	34/M	Tingling in the LUL / 8 months	ACS	Hypochromatic, anhydrotic and hypo-anesthetic macule in the left frontal region, left distal madarosis	Enlargement and electric shock-like pain on the right common fibular and left ulnar nerves	3	3	4	Negative
4	38/F	Left leg pain / 3 months	DVT	Hypochromatic, anesthetic macule with incomplete endogenous histamine test on left knee	Enlargement and electric shock-like pain on the left common fibular and posterior tibial nerves	3	4	5	Positive
5	64/F	Left leg pain / 2 years	AAO	Left dropped foot, hypochromatic anesthetic macules with incomplete endogenous histamine test on the right knee, anesthetic xerotic plaque on the left foot	Enlargement and electric shock-like pain on the left common fibular	3	6	6	Positive
6	63/M	Left leg pain / 6 years	AAO	Left dropped foot; hypochromatic and hypoaesthetic macules with incomplete endogenous histamine test on the knees and elbows	Enlargement of ulnars, common fibulars and posterior tibials nerves	6	3	4	Positive
7	75/M	Infected ulcer / 10 years	Venous ulcer	Bilateral ulnar claw, bilateral trophic plantar ulcers, amyotrophy, lobule infiltration and bone resorption	Enlargement of common fibulars and posterior tibials nerves	4	3	5	Negative

Legend: AAO acute arterial occlusion; ACS acute coronary symdrom; CSA cross-sectional area; DVT deep vein thrombosis; LUL left upper limb.