Fig. 2.

β-lactamases identified in meropenem-nonsusceptible Enterobacterales isolates collected in ten Latin American countries as part of the ATLAS global surveillance program from 2017 to 2019LA, Latin America; AR, Argentina; BR, Brazil; CL, Chile; CO, Colombia; CR, Costa Rica; GT, Guatemala; MX, Mexico; PA, Panama; VE, Venezuela; Cpase, carbapenemase; ESBL, extended-spectrum β-lactamase; None detected, no gene encoding an acquired β-lactamase was detected by PCR. ESBL (cpase-) included isolates carrying CTX-M-type [CTX-M-15 (n = 28), CTX-M-2 (n = 8), CTX-M-15 and CTX-M-2 or TEM-type ESBL (n = 7), CTX-M-1 group (n = 7), CTX-M-8 (n = 1)] and SHV-type (n = 1) ESBLs that were assumed to harbor permeability defects. One meropenem-nonsusceptible (MEM-NS) isolate collected in Guatemala was not molecularly characterized for β-lactamase genes. No MEM-NS Enterobacterales isolates were collected in the Dominican Republic during the surveyed time period.