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. 2022 Aug 20;13:427. doi: 10.1186/s13287-022-03109-2

Fig. 4.

Fig. 4

Effect of ADSC-secretome transplantation on autophagy-related pathway PI3K/Akt/mTOR protein and mRNA levels. a: Representative western blot analysis of p-Akt, Akt, p-mTOR, and mTOR. bc: Quantification of p-Akt/Akt and p-mTOR/mTOR. ef: RT-qPCR results showing PI3K, Akt, and mTOR mRNA levels. **P < 0.01, vs. IRI group. ##P < 0.01, vs. DMEM group. IRI: ischemia–reperfusion injury; ADSC-sec: adipose-derived mesenchymal stromal cell-secretome; and ADSCs: adipose-derived mesenchymal stromal cells