Table 2.
Hospital and tumour characteristics according to annual hospital volume of patients with metastatic colorectal cancer
| First quartile n = 2,328 |
Second quartile n = 2,591 |
Third quartile n = 2,531 |
Fourth quartile n = 2,518 |
All n = 9,968 | P-value* | ||
|---|---|---|---|---|---|---|---|
| Hospital level | University | 79 (3%) | 492 (19%) | 669 (26%) | 1,928 (77%) | 3,168 (32%) | < 0.001 |
| Non-university | 2,249 (97%) | 2,099 (81%) | 1,862 (74%) | 590 (23%) | 6,800 (68%) | ||
| Hospital region | 1 | 221 (9%) | 370 (14%) | 635 (25%) | 741 (29%) | 1,967 (20%) | < 0.001 |
| 2 | 505 (22%) | 608 (23%) | 869 (34%) | 273 (11%) | 2,255 (23%) | ||
| 3 | 370 (16%) | 449 (17%) | 231 (9%) | 0 (0%) | 1,050 (11%) | ||
| 4 | 390 (17%) | 459 (18%) | 407 (16%) | 763 (30%) | 2,019 (20%) | ||
| 5 | 390 (17%) | 401 (15%) | 288 (11%) | 741 (29%) | 1,820 (18%) | ||
| 6 | 452 (19%) | 304 (12%) | 101 (4%) | 0 (0%) | 857 (9%) | ||
| Primary tumour location | Right colon | 615 (26%) | 637 (25%) | 643 (25%) | 676 (27%) | 2,568 (26%) | < 0.001 |
| Transverse colon | 314 (13%) | 292 (11%) | 316 (12%) | 306 (12%) | 1,227 (12%) | ||
| Left colon | 743 (32%) | 761 (29%) | 732 (29%) | 673 (27%) | 2,912 (29%) | ||
| Unknown location in colon | 21 (1%) | 19 (1%) | 9 (0%) | 19 (1%) | 68 (1%) | ||
| Rectum | 625 (27%) | 882 (34%) | 831 (33%) | 844 (34%) | 3,193 (32%) | ||
| Pretherapeutic multidisciplinary team conference | Yes | 1,507 (65%) | 1,967 (76%) | 1,950 (77%) | 2,011 (80%) | 7,435 (75%) | < 0.001 |
| No | 812 (35%) | 621 (24%) | 570 (23%) | 498 (20%) | 2,510 (25%) | ||
| Missing | 8 (0%) | 3 (0%) | 3 (0%) | 9 (0%) | 23 (0%) | ||
| Resection of primary tumour | No | 1,128 (48%) | 1,349 (52%) | 1,397 (55%) | 1,322 (53%) | 5,196 (52%) | < 0.001 |
| Yes | 1,199 (52%) | 1,242 (48%) | 1,135 (45%) | 1,196 (47%) | 4,772 (48%) | ||
| cT | 1–3 | 659 (28%) | 959 (37%) | 824 (33%) | 824 (34%) | 3,264 (33%) | < 0.001 |
| 4 | 564 (24%) | 757 (29%) | 735 (29%) | 795 (32%) | 2,849 (29%) | ||
| X | 619 (27%) | 485 (19%) | 500 (20%) | 611 (24%) | 2,218 (22%) | ||
| Missing | 486 (21%) | 290 (15%) | 472 (19%) | 288 (11%) | 1,637 (16%) | ||
| cN | 0 | 450 (19%) | 531 (20%) | 413 (16%) | 401 (16%) | 1,795 (18%) | < 0.001 |
| 1–2 | 1,099 (47%) | 1,434 (55%) | 1,521 (60%) | 1,362 (54%) | 5,414 (54%) | ||
| X | 660 (28%) | 543 (21%) | 540 (21%) | 702 (28%) | 2,447 (25%) | ||
| Missing | 119 (5%) | 83 (3%) | 57 (2%) | 53 (2%) | 312 (3%) | ||
| Metastatic location | Liver | 744 (32%) | 913 (35%) | 908 (36%) | 805 (32%) | 3,370 (34%) | < 0.001 |
| Lung | 205 (9%) | 176 (7%) | 170 (7%) | 128 (5%) | 679 (7%) | ||
| Peritoneum | 62 (3%) | 70 (3%) | 85 (3%) | 111 (4%) | 328 (3%) | ||
| Other | 73 (3%) | 93 (4%) | 83 (3%) | 105 (4%) | 354 (4%) | ||
| Multiple locations | 1,244 (53%) | 1,339 (52%) | 1,285 (51%) | 1,369 (54%) | 5,237 (53%) | ||
Includes 9,968 patients diagnosed with metastatic colorectal cancer in 2009–2016 in Sweden
* From chi square test
Abbreviations: cN (clinical nodal status), CT (clinical tumour status)