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. 2022 Aug 20;4(4):fcac196. doi: 10.1093/braincomms/fcac196

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© The Author(s) 2022. Published by Oxford University Press on behalf of the Guarantors of Brain.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Targeted immunotherapies against soluble biomarkers. *Tacrolimus is not selectively directed against CXCL-10 but it has been reported to decrease intrathecal CXCL-10 levels. APRIL, proliferation-inducing ligand; BAFF, B-cell-activating factor; CXCL, C-X-C motif chemokine; DC, dendritic cells; FcRn, neonatal Fc receptor; IFN, interferon; IgG, immunoglobulin G; IL, interleukin; IL-R, interleukin receptor; MAC, membrane attack complex; NMDAR, N-methyl-D-aspartate receptor; TGF, transforming growth factor; Th, T-helper cells; TNF, tumour necrosis factor.