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. 2022 Aug 16;15:2497–2510. doi: 10.2147/DMSO.S362071

Table 4.

Forward Transitions of MetS States by Different Factors: Univariate Models [Hazard Ratios (95% CI)]

Variables FMD→MMD FMD→SMD FMD→MetS MMD→SMD MMD→MetS SMD→MetS
Gender 1.26(0.94,1.68) 1.08(0.75,1.56) 0.67(0.39,1.15) 1.02(0.83,1.24) 1.01(0.79,1.30) 0.95(0.80,1.12)
Age (year)
 55~64 1.03(0.75,1.41) 1.02(0.67,1.54) 1.35(0.76,2.39) 1.01(0.80,1.26) 1.23(0.92,1.63) 0.98(0.81,1.19)
 ≥65 1.05(0.71,1.56) 1.15(0.70,1.89) 0.67(0.27,1.65) 0.98(0.75,1.29) 1.04(0.74,1.48) 1.02(0.82,1.26)
Marital status 0.93(0.49,1.76) 0.76(0.31,1.86) 1.35(0.49,3.74) 0.99(0.71,1.39) 0.79(0.50,1.25) 0.83(0.64,1.08)
Education
 Primary school 0.99(0.70,1.43) 1.25(0.79,1.98) 1.01(0.49,2.07) 1.14(0.89,1.46) 1.06(0.77,1.46) 0.99(0.80,1.23)
 Junior high school 0.91(0.62,1.32) 0.95(0.57,1.58) 1.44(0.75,2.77) 1.03(0.78,1.36) 1.01(0.71,1.44) 1.16(0.94,1.43)
 ≥Senior high school 0.72(0.40,1.28) 1.57(0.88,2.79) 0.89(0.31,2.57) 0.93(0.64,1.35) 1.37(0.92,2.05) 1.07(0.80,1.42)
Exercise
 Occasionally 1.12(0.83,1.51) 1.27(0.85,1.89) 0.76(0.42,1.38) 0.96(0.77,1.21) 1.33(0.98,1.80) 1.10(0.89,1.37)
 Little 0.76(0.45,1.25) 1.33(0.76,2.32) 1.07(0.49,2.35) 0.99(0.75,1.30) 1.91(1.37,2.65)* 1.56(1.27,1.91)*
Sleep time(h)
 6–8 1.03(0.72,1.46) 1.05(0.67,1.63) 1.26(0.65,2.47) 1.06(0.84,1.36) 1.09(0.81,1.47) 1.01(0.83,1.24)
 ≥8 1.10(0.75,1.60) 0.95(0.58,1.56) 1.13(0.54,2.38) 1.03(0.79,1.34) 0.92(0.66,1.28) 1.10(0.89,1.36)
Smoke 1.13(0.84,1.51) 1.16(0.80,1.70) 0.60(0.32,1.13) 1.00(0.81,1.24) 1.40(1.08,1.80)* 1.10(0.92,1.32)
Drink 1.13(0.85,1.51) 1.31(0.91,1.90) 0.68(0.38,1.19) 1.08(0.88,1.32) 1.10(0.85,1.41) 1.21(1.02,1.43)*
Depression 0.91(0.67,1.22) 0.74(0.50,1.10) 1.33(0.77,2.28) 1.05(0.86,1.29) 0.97(0.75,1.26) 1.00(0.85,1.19)
Functional loss 0.69(0.48,0.99)* 1.40(0.95,2.08) 1.50(0.85,2.65) 0.95(0.75,1.20) 0.93(0.69,1.24) 0.95(0.79,1.16)
Hyperuricemia 1.19(0.67,2.09) 1.89(1.04,3.44)* 0.63(0.15,2.59) 1.13(0.72,1.77) 1.51 (0.92,2.46) 1.22(0.90,1.66)
BMI level
 Thin 1.15(0.80,1.64) 0.52(0.28,0.97)* 1.04(0.52,2.08) 0.78(0.55,1.10) 0.68(0.41,1.10) 0.67 (0.42,1.07)
 Overweight/Obesity 0.83(0.42,1.62) 1.87(1.05,3.35)* 0.63(0.15,2.61) 0.96(0.74,1.24) 1.79(1.36,2.36)* 1.77(1.49,2.09)*
High LDL-C 0.89(0.65,1.23) 0.89(0.59,1.35) 1.34(0.76,2.34) 0.97(0.78,1.20) 1.27 (0.98,1.63) 1.18(1.01,1.40)*
High HbA1c 0.96(0.43,2.16) 0.52(0.13,2.10) 1.14(0.28,4.68) 1.17(0.72,1.90) 0.95 (0.49,1.84) 0.96 (0.64,1.44)
High TC 0.73(0.45,1.19) 1.13(0.67,1.92) 1.42(0.69,2.90) 0.85(0.63,1.16) 0.90 (0.62,1.31) 1.07 (0.87,1.30)
High CRP 1.06(0.50,2.26) 0.99(0.37,2.70) 1.06(0.26,4.38) 1.08(0.73,1.61) 0.85 (0.49,1.46) 1.11 (0.79,1.55)

Note: *P < 0.05.

Abbreviations: FMD, free of metabolic disorder; MMD, mild metabolic disorder; SMD, severe metabolic disorder; MetS, metabolic syndrome; BMI, body Mass Index; LDL-C, low density lipoprotein cholesterol; HbA1c, glycated hemoglobin; TC, total cholesterol; CRP, C-reactive protein; CI, confidence interval.