Table 6.
Forward and Backward Transitions of MetS States by Different Factors: Multivariate Models [Hazard Ratios (95% CI)]
| Variables | Forward Transitions | Backward Transitions | |||||
|---|---|---|---|---|---|---|---|
| FMD→SMD | MMD→MetS | SMD→MetS | SMD→FMD | SMD→MMD | MetS→MMD | MetS→SMD | |
| Gender | 0.74(0.42,1.32) | 0.74(0.53,1.05) | 0.75(0.59,0.95)* | 1.93(1.03,3.64)* | 1.40(1.05,1.86)* | 2.35(1.60,3.44)* | 1.34(1.04,1.72)* |
| Age | |||||||
| 55~64 | 1.22(0.77,1.91) | 1.31(0.97,1.76) | 1.08(0.88,1.32) | 0.64(0.36,1.15) | 1.02(0.79,1.32) | 0.77(0.55,1.09) | 0.93(0.76,1.15) |
| ≥65 | 1.33(0.77,2.28) | 1.18(0.81,1.72) | 1.23(0.98,1.55) | 0.43(0.22,0.86)* | 0.92(0.68,1.25) | 0.81(0.55,1.19) | 0.94(0.74,1.18) |
| Exercise | |||||||
| Occasionally | 1.24(0.82,1.89) | 1.30(0.95,1.76) | 1.06(0.86,1.32) | 1.39(0.80,2.41) | 0.93(0.73,1.18) | 0.93(0.65,1.33) | 0.88(0.71,1.09) |
| Little | 1.36(0.74,2.50) | 1.60(1.14,2.26)* | 1.36(1.10,1.69)* | 0.81(0.39,1.6) | 0.67(0.50,0.89)* | 0.81(0.56,1.16) | 0.88(0.71,1.09) |
| Smoke | 1.32(0.81,2.15) | 1.66(1.22,2.26)* | 1.16(0.93,1.45) | 0.56(0.30,1.07) | 0.90(0.68,1.18) | 0.80(0.53,1.21) | 0.97(0.75,1.24) |
| Drink | 1.32(0.87,2.02) | 1.10(0.83,1.46) | 1.30(1.07,1.57)* | 0.75(0.42,1.34) | 0.76(0.59,0.98)* | 0.70(0.48,1.02) | 1.03(0.83,1.28) |
| Functional loss | 1.37(0.91,2.06) | 0.95(0.71,1.28) | 0.99(0.81,1.20) | 1.03(0.60,1.78) | 0.95(0.74,1.21) | 1.21(0.89,1.66) | 0.97(0.80,1.19) |
| Hyperuricemia | 2.01(1.07,3.76)* | 1.40(0.84,2.33) | 1.08(0.78,1.48) | 0.89(0.27,2.90) | 0.76(0.45,1.29) | 0.71(0.40,1.26) | 0.74(0.54,1.03) |
| BMI level | |||||||
| Thin | 0.53(0.28,1.01) | 0.65(0.40,1.08) | 0.66(0.41,1.06) | 2.44(1.29,4.59)* | 1.43(1.01,2.01)* | 1.28(0.56,2.95) | 1.51(0.88,2.61) |
| Overweight/Obesity | 1.93(1.06.3.53)* | 1.68(1.25,2.25)* | 1.68(1.41,2.00)* | 0.15(0.06,0.37)* | 0.44(0.33,0.58)* | 0.36(0.27,0.48)* | 0.76(0.63,0.90)* |
| High LDL-C | 0.90(0.59,1.37) | 1.19(0.92,1.55) | 1.11(0.94,1.32) | 0.67(0.39,1.18) | 0.97(0.77,1.22) | 1.00(0.74,1.35) | 0.98(0.82,1.17) |
| High HbA1c | 0.47(0.11,1.95) | 1.07(0.54,2.10) | 0.97(0.64,1.46) | 0.28(0.04,2.08) | 0.79(0.45,1.37) | 0.54(0.29,1.03) | 0.45(0.30,0.67)* |
Note: *P < 0.05.
Abbreviations: FMD, free of metabolic disorder; MMD, mild metabolic disorder; SMD, severe metabolic disorder; MetS, metabolic syndrome; BMI, body Mass Index; LDL-C, low density lipoprotein cholesterol; HbA1c, glycated hemoglobin; TC, total cholesterol; CI, confidence interval.