TABLE 4.

Effect of the extract on serum biochemical factors

Factors	Treatments
	Vehicle	Extract 400 (g/kg)	CUS + Saline	CUS + Extract 400 (g/kg)
AST (IU/L)	192 ± 9	166 ± 6	284 ± 3** ##	229 ± 4** ### ^^^
ALT (IU/L)	96.4 ± 3.9	90 ± 2.6	168 ± 2*** ###	121 ± 2*** ### ^^^
Urea (mg/dl)	34.6 ± 1.5	25 ± 1**	53 ± 2*** ###	41 ± 0.7 ### ^^^
Creatin (mg/dl)	0.38 ± 0.01	0.36 ± 0.02	0.46 ± .02	0.38 ± .02
Glucose (mg/dl)	101.8 ± 2.4	93 ± 3	149 ± 5*** ###	117 ± 2* ## ^^^
LDL (mg/dl)	24.4 ± 0.6	25 ± 1	34 ± 0.6*** ###	28 ± 0.6*** ### ^^^
HDL (mg/dl)	55 ± 2	49 ± 1	45 ± 2*	48 ± 3
TG (mg/dl)	65 ± 4	62 ± 1	69 ± 2	63 ± 1
Cholesterol (mg/dl)	53.4 ± 1.3	52 ± 1	69 ± 3** ##	64 ± 2* ##

Values are given as mean ± SEM.

^* p < 0.05.

^** p < 0.01, and.

^*** p < 0.001 in comparison with the vehicle group.

^## p < 0.01 and.

^### p < 0.001 versus the extract group (400 g/kg).

^{^^^} p < 0.001 compared to CUS+Saline group.

CUS: chronic unpredictable stress; extract: Origanum vulgare L. extract.