Figure 4.

Decision curve analysis comparing the clinical utility of our model (red dotted line) to the International Task Force Consensus Statement algorithm (blue dotted line). The clinical utility of both treatment strategies is compared by plotting the net benefit (y axis) for a range of potential implantable cardioverter-defibrillator placement thresholds based on the 5-year risk of VA (x axis). Our model showed the highest net benefit for all potential thresholds (ranging from 2.5% to 27.5%). This indicates that our model would result in the highest weighted balance of appropriate vs. inappropriate implantable cardioverter-defibrillator placements, regardless of the clinically preferred risk threshold. ICD, implantable cardioverter-defibrillator; ITFC, International Task Force Consensus Statement.