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. 2022 Feb 10;58(7):1361–1380. doi: 10.1007/s10597-022-00948-4

Table 3.

Factors with significance, effect size and type of analysis in the studies included in the systematic review that used WHOQoL-BREF or QLESQ−SF to assess QoL

Author (year). Measurement Type of analysis/effect size Factors with significance
Overall QoL General health Physical health Psychological Social relationship Environment

Angermeyer et al. (2006)

WHOQoL-BREF

Multivariate small to large n.s n.s Age of spouse (d = 1.22, p = .01), Depression symptoms (d = .97, p = .01) Depression symptoms (d = .92, p = .05), Living situation (d = .75, p = .042), Sense of coherence (d = .76, p = .036) Patient’s functioning (d = .87, p = .05) Patient’s diagnosis of schizophrenia (d = .44, p = .01)

Chou et al. (2009)

WHOQoL-BREF

Multivariate small to large Family support (β = .21, d = .47, p < .05), Stigma (β =  − .23, d = .54, p < .05), Physical health (β =  − .39, d = .93, p < .05) n.s n.s n.s n.s n.s

Gómez-de-Regil et al. (2014)

WHOQoL-BREF

Bivariate small to large GAF (r = .30, p < .01), GHQ-28 (r = .74, p < 0.01), Somatic symptoms (r = .64, p < .01), Anxiety-insomnia (r = .54, p < .01), Social dysfunction (r = .58, p < .01), Depression (r = .52, p < .01), Consequences-relative (r = .35, p < .01), Control-cure of illness (r = .28, p < .05) n.s n.s n.s n.s n.s
Multivariate small to large GAF (β =  − .08, p = .015), GHQ-28 (β =  − .44, p < .001); Illness perception (β =  − .13, p = .003), Consequences-patient (β =  − .0.19, p = .041), Consequences-relative (β =  − .26, p = .011), Control-cure of illness (β =  − .25, p = .005), Control-cure by relative (β =  − .16, p = .055) n.s n.s n.s n.s n.s

Kate et al. (2013)

WHOQoL-BREF

Bivariate small to medium n.s Tension (r =  − .25 p = .012) Tension (r =  − .22, p = .027), Worrying-urging (r = .23, p = .019), Supervision (r =  − .23, p = .021), Involvement Evaluation (r = .33, p = .001) Tension (r =  − .29, p = .002) Tension (r =  − .28, p = .004) Tension (r =  − .29, p = .003)

Li et al. (2007)

WHOQoL-BREF

Bivariate small to large Household income (r = .28, p < .01), Physical health (r = .34, p < .01), Caregiver burden (r = .25, p < .05), Demand burden (r = .29, p < .01), Stress burden (r = .37, p < .01) Physical health (r = .41, p < .01) Education level (r = .23, p < .05), Household income (r = .28, p < .01), Physical health (r = .51, p < .01), Caregiver burden (r = .21, p < .05), Demand burden (r = .21, p < .05), Stress burden (r = .35, p < .01) Education level (r = .21, p < .05), Physical health (r = .38, p < .01), Caregiver burden (r = .38, p < .01), Demand burden (r = .35, p < .01), Stress burden (r = .50, p < .01) Physical health (r = .24, p < .01), Caregiver burden (r = .21, p < .05), Demand burden (r = .21, p < .05), Stress burden (r = .35, p < .01) Household income (r = .36, p < .01), Physical health (r = .31, p < .01), Caregiver burden (r = .30, p < .01), Demand burden (r = .36, p < .05), Stress burden (r = .39, p < .01)
Multivariate small to large Physical health (β = .385, p = .000), Household income (β = .24, p = .012) n.s n.s n.s n.s n.s

Margetic et al. (2013)

QLESQ − SF

Bivariate small to medium Age (r =  − .46, p = .0001), Marital status (d = .27, p = .003), Education level (d = .24, p = .011), Relationship to the patient (d = .56, p = .0001) n.s n.s n.s n.s n.s

Mizuno et al. (2012)

WHOQoL-BREF

Medium to large

Bivariate medium to large Age (d = .84, p = .08), Sense of coherence (d = 1.10, p = .011) n.s no significant factors no significant factors Sense of coherence (d = 1.05, p = .003) Age (d = .72, p = .032), Sense of coherence (d = .92, p = .02)
Multivariate medium to large n.s n.s no significant factors Age (β = .42, p = .013, Living situation (β =  − .34, p = .042) no significant factors Age (β = .35, p = .032)

ZamZam et al. (2011)

WHOQoL-BREF

Bivariate small to large n.s n.s Gender (d = .38, p = .039), Educational level (d = .76, p = .001), Employment status (d = .56, p = .003), Medical problems (d = .89, p = .000), Relationship to the patient (d = .51, p = .006), Duration of illness (d = .45, p = .016), Onset of illness (d = .66, p = .025), Attending day care (d = .65, p = .024), BPRS (r = .30, p = .013) Patient’s employment (d = .62, p = .012), Patient’s educational level (d = .52, p = .008), Caregiver’s educational level (d = .57, p = .004), Caregiver’s employment (d = .38, p = .041), Medical problems (d = .69, p = .001), SRRS (r =  − .21, p = .027), Duration of illness (d = .42, p = .024), Attending day care (d = .63, p = .028) Caregiver’s educational level (d = .59, p = .006), Patient’s number of hospitalisations (d = .73, p = .017), Duration of illness (d = .68, p = .000), Onset of illness (d = .66, p = .027), Attending day care (d = .64, p = .025) Caregiver’s educational level (d = .76, p = .001), Medical problems (d = .47, p = .023), SRRS (r =  − .23, p = .012), Patient’s number of hospitalisations (d = .74, p = .037), Duration of illness (d = .43, p = .022), Attending day care (d = .92, p = .003), BPRS (r =  − .20, p = .031)
Multivariate small to large n.s n.s Caregivers having medical problems (β = -.286, p = .001), BPRS (β =  − .204, p = .017) Caregivers having medical problems (β = -.197, p = .031), Patient’s educational level (β = .204, p = .026) Duration of illness (β =  − .207, p = .029), Carer’s educational level (β = .203, p = .028), Onset of illness (β = .195, p = .040), Patient’s educational level (β = .182, p = .046) Attending day care (β = .228, p = .009), Carer’s educational level (β = .269, p = .003), SRRS (β =  − .182, p = .037)

n.s. not specified, GAF Global Assessment of Functioning, GHQ-28 general health questionnaire, BPRS Brief Psychiatric Rating Scale, SRRS Social Readjustment Rating Scale