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. 2022 Aug 20;12:340. doi: 10.1038/s41398-022-02071-0

Fig. 1. SZ-associated differential methylation.

Fig. 1

A Probability plot showing that the analysis for sites at which DNAm differed between SZ and NPC subjects is enriched in small p values compared to what would be expected by chance. The y = x line represents the distribution of p values that would be expected by chance. B Manhattan plot showing that the DNAm differed between subjects with SZ and NPC subjects at many DNAm sites, and the sites were distributed across many autosomes. The horizontal lines represent FDR cutoff of q = 0.1 (bottom) and q = 0.05 (top). DNAm DNA methylation, SZ schizophrenia, NPC non-psychiatric comparison, FDR false discovery rate.