Table 2.

Characteristics of studies included only in the qualitative synthesis ND: no data.

Publication data		GR 1	GR 2	Design	Demography				No. of patients	Definition of clinical success	Definition of recurrence	Mean follow up (months)
First author	Year of publication				Country, institution	Age (years) group surgical excision		Female ratio % Group 1
						Mean	Standard deviation
Chaugule et al.36	2017	IFN	5-FU	Retrospective, interventional series	USA—The New York Eye Cancer Center	ND	ND	ND	6	Clinical resolution of the tumor, defined on slit-lamp examination	Reappearance of the lesion at a similar location, after complete resolution	IFN: 8.8; 5-FU: 18
Kusumesh et al.37	2017	IFN	MMC	Retrospective, comparative study	Patna, India—Cornea Services, Regional Institute of Ophthalmology, Indira Gandhi Institute of Medical Sciences	59.5	14.55	ND	51	Total disappearance of lesions with clear visibility of underlying structures	Reappearance of a tumor at the same location or at any other location after complete resolution	IFN: 22.2 MMC: 23.6
Venkateswaran et al.38	2018	IFN	5-FU	Retrospective, comparative, interventional case series	USA—University of Miami, Bascom Palmer Eye Institute	67.5	11	ND	102	Disappearance of the lesion clinically and/or by AS-OCT	Reappearance of a tumor at the same/similar location or at any part of the ocular surface after complete resolution	5-FU: 15.8 IFN: 20.9