Table 4.
Adverse events
| Group P | Group PK1 | Group PK2 | Group PK3 | P value | |
|---|---|---|---|---|---|
| Injection pain | 3 (4.6%) | 7 (10.8%) | 2 (3.1%) | 1 (1.5%) | 0.149 |
| Hypoxemia | 14 (21.5%) | 16 (24.6%) | 23 (35.4%) | 16 (24.6%) | 0.297 |
| Hypotension | 11 (16.9%) | 8 (12.3%) | 3 (4.6%) | 4 (6.2%) | 0.072 |
| Cough | 46 (70.8%) | 34 (52.3%) | 37 (56.9%) | 31 (47.7%)※ | 0.048 |
| Body movement | 54 (83.1%) | 55 (84.6%) | 42 (64.6%) | 39 (60.0%)※† | 0.001 |
| Dizziness | 7 (10.8%) | 9 (13.8%) | 6 (9.2%) | 11 (16.9%) | 0.563 |
| Excessive oral secretion | 0 (0%) | 0 (0%) | 0 (0%) | 2 (3.1%) | 0.247 |
| Hypertension | 0 (0%) | 1 (1.5%) | 0 (0%) | 0 (0%) | 1.000 |
| Arrhythmia | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 1.000 |
| Nausea and vomiting | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 1.000 |
| Apnea | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 1.000 |
Data are presented as number (%); ※P < 0.05 compared with group P, †P < 0.05 compared with group PK1