Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 May 5;122(8):1314–1325. doi: 10.1055/a-1759-9962

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ )

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.

PMC Copyright notice

Fig. 3. — Thromboelastometric analysis with adherent EC microcarriers using human whole blood samples. (A) Representative image of CD31-positive cells ( brown, black arrows ) surrounding the surface of Cytodex 3 EC microcarriers ( white arrows ) in a blood clot obtained by ROTEM. Scale bar = 100 µm. (B) Clotting time (CT) and (C) lysis time (LT) in the presence of 58, 115, 230, or 460 nmol/L of rivaroxaban. (D) CT and (E) LT in the presence of 0.4, 0.9, 1.8, or 3.7 µmol/L of CM-352 and 460 nmol/L of rivaroxaban. (F) CT and (G) LT in the presence of MMP-10 (200 nmol/L), rivaroxaban (460 nmol/L), and CM-352 (1.8 µmol/L). CT and LT times expressed in seconds (s) are presented in the graphs. Mean ± SD, * p < 0.05 and ** p < 0.01 vs. 0 nmol/L; ^# p < 0.05 and ^## p < 0.01 vs. 0 µmol/L; ^† p < 0.05 and ^†† p < 0.01 vs. Ctrl; ^‡‡ p < 0.01 vs. MMP-10; ^¥ p < 0.05 vs. MMP-10 + Riva, using Kruskal–Wallis and Mann–Whitney U-test, n ≥ 3/group. EC, endothelial cell; ROTEM, rotational thromboelastometry; SD, standard deviation; TAFI, thrombin-activatable fibrinolysis inhibitor.