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. 2022 Aug 22;44(5):2393–2425. doi: 10.1007/s11357-022-00631-2

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© The Author(s), under exclusive licence to American Aging Association 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 18 — Evaluated outcome of the molecular and mutational properties of G446S. (A) Calculated vibrational Entropy Energy of G446S and its pictorial representation. (B) Illustrated interatomic interactions of wild type to mutant type G446S mutation. For this analysis, the DynaMut server was used to evaluate the molecular and mutational properties of S371L [52]. For the analysis, we used a model PDB file (PDB ID: 7QO7)