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. 2022 Aug 22;44(5):2393–2425. doi: 10.1007/s11357-022-00631-2

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© The Author(s), under exclusive licence to American Aging Association 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 21 — The graphical image shows the emerging mutations of RBD (S-glycoprotein) of the Omicron. It is also shown how it affects flexibility changes and stability alteration due to amino acid point mutation. (A) The schematic diagram illustrates the emerging mutations of RBD (S-glycoprotein) of the Omicron and their effects on stability (stabilizing event or destabilizing) (B) The schematic diagram shows the emerging mutations of RBD (S-glycoprotein) of the Omicron and their impact on flexibility