Table 1.

Mutational landscape of Omicron variant

Mutation	Mutation site	Remarks
A67V	NTD of Spike protein	Ala $\stackrel{67}{\to }$ Val
Δ69–70	Spike protein deletion	Deletion mutations
T95I	NTD of Spike protein	Thr $\stackrel{95}{\to }$ Ile
G142D	NTD of Spike protein	Gly $\stackrel{142}{\to }$ Asp
Δ143–145	Spike protein deletion	Deletion mutations
Δ211	Spike protein deletion	Deletion mutations
L212I	NTD of Spike glycoprotein	Leu $\stackrel{212}{\to }$ Ile
ins214EPE	Insertion in Spike glycoprotein	Insertions of Glu, Pro, and Glu amino acids
T547K	Spike glycoprotein	Thr $\stackrel{547}{\to }$ Lys
D614G	Spike glycoprotein	Asp $\stackrel{614}{\to }$ Gly
H655Y	Spike glycoprotein	His $\stackrel{655}{\to }$ Tyr
N679K	Spike glycoprotein	Asn $\stackrel{679}{\to }$ Lys
P681H	Spike glycoprotein	Pro $\stackrel{681}{\to }$ His
N764K	Spike glycoprotein	Asn $\stackrel{764}{\to }$ Lys
D796Y	Fusion peptide in Spike protein	Asp $\stackrel{796}{\to }$ Tyr
N856K	Spike glycoprotein	Asn $\stackrel{856}{\to }$ Lys
Q954H	HR1 in Spike protein	Gln $\stackrel{954}{\to }$ His
N969K	HR1 in Spike protein	Asn $\stackrel{969}{\to }$ Lys
L981F	HR1 in Spike protein	Leu $\stackrel{981}{\to }$ Phe
G339D	RBD in Spike protein	Gly $\stackrel{339}{\to }$ Asp
S371L	RBD in Spike protein	Ser $\stackrel{371}{\to }$ Leu
S373P	RBD in Spike protein	Ser $\stackrel{373}{\to }$ Pro
S375F	RBD in Spike protein	Ser $\stackrel{375}{\to }$ Phe
K417N	RBD in Spike protein	Lys $\stackrel{417}{\to }$ Asn
N440K	RBD in Spike protein	Asn $\stackrel{440}{\to }$ Lys
G446S	RBD in Spike protein	Gly $\stackrel{446}{\to }$ Ser
S477N	RBD in Spike protein	Ser $\stackrel{477}{\to }$ Asn
T478K	RBD in Spike protein	Thr $\stackrel{478}{\to }$ Lys
E484A	RBD in Spike protein	Glu $\stackrel{484}{\to }$ Ala
Q493K	RBD in Spike protein	Gln $\stackrel{493}{\to }$ Lys
G496S	RBD in Spike protein	Gly $\stackrel{496}{\to }$ Ser
Q498R	RBD in Spike protein	Gln $\stackrel{498}{\to }$ Arg
N501Y	RBD in Spike protein	Asn $\stackrel{501}{\to }$ Tyr
Y505H	RBD in Spike protein	Tyr $\stackrel{505}{\to }$ His
K38R	ORF1a	Lys $\stackrel{38}{\to }$ Arg
V1069I	ORF1a	Val $\stackrel{1069}{\to }$ Ile
Δ1265	Deletion in ORF1a	Deletion mutation
L1266I	ORF1a	Leu $\stackrel{1266}{\to }$ Ile
A1892T	ORF1a	Ala $\stackrel{1892}{\to }$ Thr
T492I	ORF1a	Thr $\stackrel{492}{\to }$ Ile
P132H	ORF1a	Pro $\stackrel{132}{\to }$ His
Δ105–107,	Deletions in ORF1a	Deletion mutations
A189V	ORF1a	Ala $\stackrel{189}{\to }$ Val
P323L	ORF1b	Pro $\stackrel{323}{\to }$ Leu
I42V	ORF1b	Ile $\stackrel{42}{\to }$ Val
T9I	Envelope protein	Thr $\stackrel{9}{\to }$ Ile
D3G	Nucleoprotein	Asp $\stackrel{3}{\to }$ Gly
Q19E	Nucleoprotein	Gln $\stackrel{19}{\to }$ Glu
A63T	Nucleoprotein	Ala $\stackrel{63}{\to }$ Thr
P13L	Nucleocapsid protein	Pro $\stackrel{13}{\to }$ Leu
Δ31–33	Deletions in Nucleocapsid protein	Deletion mutations
R203K	Nucleocapsid protein	Arg $\stackrel{203}{\to }$ Lys
G204R	Nucleocapsid protein	Gly $\stackrel{204}{\to }$ Arg