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. 2022 Aug 21;12:14247. doi: 10.1038/s41598-022-18552-7

Table 3.

Comparison of tacrolimus dose-adjusted area under the 12-h curve at day 7 post-kidney transplantation among groups.

Group Mean rank Kruskal–Wallis H P value
EXplb (n = 12) 10.2 19.704  < 0.001
EXdtz (n = 11) 18.8
NEplb (n = 8) 25.4
NEdtz (n = 9) 32.0
Pairwise comparison Mean rank difference Standard error P valuea
EXplb–NEdtz − 21.83 5.16  < 0.001
EXplb–NEplb − 15.21 5.34 0.026
EXplb–EXdtz − 8.65 4.88 0.457
EXdtz–NEdtz − 13.18 5.25 0.073
EXdtz–NEplb − 6.56 5.43 1.000
NEdtz–NEplb − 6.62 5.68 1.000

EXplb CYP3A5 expressers with placebo group, EXdtz CYP3A5 expressers with diltiazem group, NEplb CYP3A5 nonexpressers with placebo group, NEdtz CYP3A5 nonexpressers with diltiazem group.

aBonferroni correction for multiple comparisons.