TABLE 1.

Basic information of active components of PD.

Source	Id	Active ingredient	OB(%)	DL
Cortex Fraxini	PD1	8-betaDGlucopyranosyloxy-7-hydroxy-6-methoxy-2H-1-benzopyran-2-one	36.76	0.42
Cortex Fraxini	PD2	AIDS214634	92.43	0.55
Coptis Chinensis	PD3	Moupinamide	86.71	0.26
Coptis Chinensis	PD4	Corchoroside A_qt	104.95	0.78
Coptis Chinensis	PD5	Berlambine	36.68	0.82
Coptis Chinensis	PD6	(R)-Canadine	55.37	0.77
Coptis Chinensis	PD7	epiberberine	43.09	0.78
Phellodendron, Coptis Chinensis	PD8	Obacunone	43.29	0.77
Phellodendron, Coptis Chinensis	PD9	berberrubine	35.74	0.73
Phellodendron, Coptis Chinensis	PD10	Worenine	45.83	0.87
Phellodendron, Coptis Chinensis	PD11	coptisine	30.67	0.86
Phellodendron, Coptis Chinensis	PD12	berberine	36.86	0.78
Phellodendron, Coptis Chinensis	PD13	palmatine	64.6	0.65
Phellodendron, Coptis Chinensis	PD14	Palmidin A	35.36	0.65
Phellodendron, Coptis Chinensis	PD15	Magnograndiolide	63.71	0.19
Phellodendron, Coptis Chinensis	PD16	quercetin	46.43	0.28
Phellodendron	PD17	thalifendine	44.41	0.73
Phellodendron	PD18	phellochin	35.41	0.82
Phellodendron	PD19	melianone	40.53	0.78
Phellodendron	PD20	dihydroniloticin	36.43	0.82
Phellodendron	PD21	campesterol	37.58	0.71
Phellodendron	PD22	Hispidone	36.18	0.83
Phellodendron	PD23	Hericenone H	39	0.63
Phellodendron	PD24	Candletoxin A	31.81	0.69
Phellodendron	PD25	Cavidine	35.64	0.81
Phellodendron	PD26	Chelerythrine	34.18	0.78
Phellodendron	PD27	Skimmianin	40.14	0.2
Phellodendron	PD28	rutaecarpine	40.3	0.6
Phellodendron	PD29	niloticin	41.41	0.82
Phellodendron	PD30	kihadanin A	31.6	0.7
Phellodendron	PD31	dihydroniloticin	36.43	0.81
Phellodendron	PD32	delta7-Dehydrosophoramine	54.45	0.25
Phellodendron	PD33	Dehydrotanshinone II A	43.76	0.4
Phellodendron	PD34	Phellopterin	40.19	0.28
Phellodendron	PD35	delta 7-stigmastenol	37.42	0.75
Phellodendron	PD36	Phellavin_qt	35.86	0.44
Phellodendron	PD37	Kihadalactone A	34.21	0.82
Phellodendron	PD38	poriferast-5-en-3beta-ol	36.91	0.75
Phellodendron	PD39	(S)-Canadine	53.83	0.77
Phellodendron	PD40	phellamurin_qt	56.6	0.39
Phellodendron	PD41	Isocorypalmine	35.77	0.59
Phellodendron	PD42	Fumarine	59.26	0.83
Pulsatilla, Phellodendron, Cortex Fraxini	PD43	beta-sitosterol	36.91	0.75
Pulsatilla, Phellodendron	PD44	Stigmasterol	43.83	0.76
Pulsatilla	PD45	β-sitosterol	33.94	0.7
Pulsatilla	PD46	ZINC01615307	56.38	0.87
Pulsatilla	PD47	3beta,23-Dihydroxy-lup-20 (29)-ene-28-O-alpha-L-rhamnopyranosyl (1–4) -beta-D-glucopyranosyl (1–6) -beta-D-glucopyranoside_qt	37.59	0.79
Pulsatilla	PD48	LAN	42.12	0.75
Pulsatilla	PD49	Aureusidin	53.42	0.24
Pulsatilla	PD50	Sitosteryl acetate	40.39	0.85
Pulsatilla	PD51	Pulchinenoside C_qt	37.79	0.76
Pulsatilla	PD52	isorhamnetin	49.6	0.31
Pulsatilla	PD53	Mairin	55.38	0.78

OB, oral bioavailability; DL, drug-likeness.