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. 2022 Aug 8;9:911845. doi: 10.3389/fcvm.2022.911845

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Copyright © 2022 Lu, Liu, Mei, Yu, Bai, Bao, Wang, Fu, Yi, Ge, Shen, Peng and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential metabolites and pathways involved in the experimental groups. (A) Venn diagram shows discriminant metabolites can be classified into regions a, b, c, d, e, f, and g. (B) Serum taurine, L-carnitine, betaine, and cystine levels change in the three comparisons. (C) Pathway analysis of differential metabolites in Venn a+d+e+g region. (D) Pathway analysis of differential metabolites in Venn b+d+f+g region. (E) Pathway analysis of differential metabolites in Venn c+e+f+g region. (F) Pathway analysis of differential metabolites in Venn b+g. ^***p < 0.01.