Table 2.

Gene set enrichment analysis of target genes for hsa- miR-223-5p.

Name	Hits	Pop Hits	List Total	Genes	Pvalue	Adjusted P-value
Gene Ontology
GO:0006699_bile_acid_biosynthetic_process	5	48	106	18160	0.0	0.0001
GO:0008284_positive_regulation_of_cell_population_proliferation	13	584	106	18160	0.0001	0.0006
GO:1902476_chloride_transmembrane_transport	6	114	106	18160	0.0001	0.0006
GO:0006303_double-strand_break_repair_via_nonhomologous_end_joining	5	96	106	18160	0.0004	0.0019
GO:0006874_cellular_calcium_ion_homeostasis	5	115	106	18160	0.0008	0.003
GO:0008543_fibroblast_growth_factor_receptor_signaling_pathway	5	133	106	18160	0.0015	0.0048
GO:0045893_positive_regulation_of_transcription,_DNA-templated	12	752	106	18160	0.0028	0.0076
GO:0030154_cell_differentiation	10	611	106	18160	0.0049	0.0116
GO:0005925_focal_adhesion	10	498	77	12816	0.0016	0.0144
GO:0034220_ion_transmembrane_transport	5	211	106	18160	0.0098	0.0207
GO:0001228_DNA-binding_transcription_activator_activity,_RNA_polymerase_II-specific	10	500	95	15238	0.002	0.0222
GO:0005125_cytokine_activity	6	222	95	15238	0.0037	0.0222
GO:0004674_protein_serinethreonine_kinase_activity	10	609	95	15238	0.0076	0.0304
GO:0007411_axon_guidance	5	246	106	18160	0.0176	0.0334
GO:0007268_chemical_synaptic_transmission	5	259	106	18160	0.0214	0.037
GO:0003677_DNA_binding	13	984	95	15238	0.0143	0.0382
GO:0003924_GTPase_activity	7	412	95	15238	0.0191	0.0382
GO:0008134_transcription_factor_binding	6	310	95	15238	0.0165	0.0382
GO:0003682_chromatin_binding	7	439	95	15238	0.0256	0.0384
GO:0005525_GTP_binding	7	427	95	15238	0.0225	0.0384
GO:0006915_apoptotic_process	8	571	106	18160	0.0244	0.0386
KEGG
hsa04010_MAPK_signaling_pathway	7	295	52	8019	0.0051	0.0153
hsa04150_mTOR_signaling_pathway	5	155	52	8019	0.0048	0.0153
hsa05205_Proteoglycans_in_cancer	5	204	52	8019	0.0141	0.0282
hsa04014_Ras_signaling_pathway	5	232	52	8019	0.0228	0.0342