Table 6.

Other sites bleeding among DOAC using patients.

Other sites bleeding
	Concurrent statin	No. of PQs	No. of events	Crude incidence rate (per 1,000 person-year) (95% CI)	Adjusted incidence rate (per 1,000 person-year) (95% CI)	Adjusted IRR (95% CI)	Adjusted IRD (per 1,000 person-year) (95% CI)
All	No statin	332259	130	1.56 (1.31–1.86)	1.88 (1.38–2.56)	1
	All intensity	238923	85	1.42 (1.14–1.78)	1.42 (1.14–1.78)	0.76 (0.52–1.11)	−0.45 (−1.12 to 0.21)
	High-intensity	79266	34	1.72 (1.20–2.45)	1.72 (1.20–2.45)	0.85 (0.52–1.41)	−0.3 (−1.24 to 0.64)
	Low-to-moderate-intensity	165474	54	1.31 (0.99–1.72)	1.31 (0.99–1.72)	0.72 (0.48–1.07)	−0.52 (−1.15 to 0.12)
Male	No statin	190084	78	1.64 (1.31–2.06)	2.06 (1.35–3.14)	1
	All intensity	135304	49	1.45 (1.08–1.94)	1.45 (1.08–1.94)	0.7 (0.42–1.18)	−0.61 (−1.58 to 0.36)
	High-intensity	45017	22	1.95 (1.26–3.02)	1.95 (1.26–3.02)	0.91 (0.47–1.73)	−0.2 (−1.54 to 1.13)
	Low-to-moderate-intensity	93569	28	1.20 (0.82–1.76)	1.20 (0.82–1.76)	0.6 (0.34–1.03)	−0.81 (−1.72 to 0.10)
Female	No statin	141669	51	1.44 (1.09–1.89)	1.39 (0.99–1.95)	1
	All intensity	103070	36	1.40 (0.99–1.97)	1.40 (0.99–1.97)	0.99 (0.61–1.61)	−0.02 (−0.70 to 0.67)
	High-intensity	34017	12	1.41 (0.77–2.60)	1.41 (0.77–2.60)	0.95 (0.47–1.95)	−0.07 (−1.09 to 0.95)
	Low-to-moderate-intensity	71558	26	1.45 (0.98–2.16)	1.45 (0.98–2.16)	1.04 (0.62–1.76)	0.06 (−0.68 to 0.81)

DOAC, direct oral anticoagulant; PQ, person-quarter; CI, confident interval; IRR, incidence rate ratio; IRD, incidence rate difference.