Table 2.
Virulence-associated genes in SR33.
| VF classes | Virulence factors | Genes |
|---|---|---|
| Fimbrial adherence determinants | Agf (thin aggregative fimbriae/curli) | csgABCDEFG, steABC |
| Lpf (long polar fimbriae) | lpfABCE | |
| Type 1 fimbriae | fimCDFHI | |
| Non-fimbrial adherence determinants | MisL | misL |
| SinH | sinH | |
| Iron uptake | Enterobactin | entABCES, fepABCDG |
| Salmochelin | iroBCN | |
| Magnesium uptake | Magnesium uptake/transporter | mgtBC |
| Macrophage inducible gene | Mig-14 | mig-14 |
| Motility | Flagella | cheWY, flgGH, fliAGMP |
| Secretion system | T3SS (SPI-1 encoded) | invABCEFGHIJ, orgABC, prgHIJK, sicAP, sipD, spaOPQRS |
| T3SS-1 translocated effectors | avrA, sipABC/sspABC, sopABDE2, sptP, slrP | |
| T3SS (SPI-2 encoded) | ssaCDEGHIJKLMNOPQRSTUV, sscAB, sseABCDE | |
| T3SS-2 translocated effectors | pipBB2, sifABH, sopD2, sseFGJK1K2L, spiC/ssaB | |
| Serum resistance | OmpA (Outer membrane protein A) | ompA |
| Others | Lipooligosaccharide | gmhA/lpcA |
| Lipopolysaccharide | gtrAB |
VF, virulence factors.