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. 2022 Aug 8;13:940768. doi: 10.3389/fphar.2022.940768

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Copyright © 2022 Chen, Zhou, Wei, Cheng, Tian, Quan, Kong, Wu and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evaluation of mouse cardiac hypertrophy models. (A) The heart appearance of sham, TAC_2w and TAC_4w group. (B)The heart weight/body weight (HW/BW) significantly increased in TAC2w and TAC4w compared to the sham group. (C)The heart mass/tibia length (HW/TL) significantly increased in TAC2w and TAC4w compared to the sham group. (D) Representative image of an echocardiographic detection of the sham, TAC_2w and TAC_4w. (E–J) Cardiac function indicators (EF, FS, LV mass, LVIDd, LVPWd) measured by echocardiography in sham, TAC_2w and TAC_4w.