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. 2022 Aug 8;16:949129. doi: 10.3389/fnins.2022.949129

TABLE 1.

Participant characteristics.

Characteristics AD (n = 26) SIVD (n = 27) NC (n = 27) P
Age, Mean ± SD (year) 66.65 ± 9.53 65.37 ± 9.93 65.04 ± 6.12 0.708
Male, N (%) 11(42.3) 18 (66.7) 10 (37.0) 0.068
Education, median (Q25, Q75) (year) 12.00 (9.00, 15.00) 12.00 (9.00, 13.00) 12.00 (9.00, 12.00) 0.163
TC, Mean ± SD (mmol/L) 4.50 ± 1.09 4.07 ± 1.46 4.06 ± 0.87 0.262
TG, median (Q25, Q75) (mmol/L) 1.20 (1.01, 1.74) 1.34 (1.03, 1.72) 1.02 (0.79, 1.38) 0.060
LDL, median (Q25, Q75) (mmol/L) 2.55 (1.92, 3.22) 1.77 (1.35, 3.18) 2.52 (1.83, 2.95) 0.414
HDL, Mean ± SD (mmol/L) 1.32 ± 0.38 1.20 ± 0.43 1.25 ± 0.38 0.537
Hypertension, N (%) 11 (42.3) 17 (63.0) 20 (74.1) 0.057
Diabetes, N (%) 6 (23.1) 7 (25.9) 9 (33.3) 0.687
Hyperlipidemia, N (%) 3 (11.5) 5 (18.5) 9 (33.3) 0.139
MMSE, Mean ± SD (score) 19.12 ± 5.69# 21.09 ± 8.32# 27.63 ± 1.28 <0.001
MoCA, Mean ± SD (score) 13.60 ± 4.87# 16.27 ± 7.32# 25.07 ± 1.04 <0.001
Fazekas WMSA burden, N (%) <0.001
High (3–6 scores) 1 (3.8)* 23 (85.7) NA
Low (0–2 scores) 25 (96.2) 4 (14.3) NA
MTA, N (%) 0.128
None to mild (0–1 scores) 8 (30.8) 14 (52.2) NA
Moderate to severe (2–4 scores) 18 (69.2) 13 (47.8) NA

Data are shown as mean ± SD and N (%).

*Compared with the subcortical ischemic vascular dementia (SIVD) group, the difference was significant (p < 0.05).

#Compared with the NC group, the difference was significant (p < 0.05).