Table 3.

The differences of the diffusivities along the axis in the fibers between early CKD patients with or without comorbidities.

	Early CKD patients with DM (N = 8)		Early CKD patients without DM (N = 10)
	Mean	SD	Mean	SD	p-value
Projection fiber
Dxx	0.0006	0.0001	0.0007	0.0001	0.0747
Dyy	0.0006	0.0002	0.0006	0.0001	0.5264
Dzz	0.0011	0.0002	0.0010	0.0001	0.9049
Association fiber
Dxx	0.0007	0.0001	0.0007	0.0001	0.3734
Dyy	0.0011	0.0001	0.0011	0.0001	0.7157
Dzz	0.0004	0.0001	0.0005	0.0001	0.5796
Subcortical fiber
Dxx	0.0011	0.0001	0.0011	0.0001	0.8137
Dyy	0.0007	0.0001	0.0007	0.0002	0.8667
Dzz	0.0006	0.0001	0.0007	0.0002	0.5735
DTI-ALPS index	1.2004	0.2321	1.3067	0.1662	0.2738
	Early CKD patients with HTN (N = 13)		Early CKD patients without HTN(N = 5)
	Mean	SD	Mean	SD	p -value
Projection fiber
Dxx	0.0006	0.0001	0.0006	0.0001	0.1235
Dyy	0.0006	0.0002	0.0006	0.0001	0.9110
Dzz	0.0011	0.0001	0.0010	0.0002	0.5258
Association fiber
Dxx	0.0007	0.0001	0.0006	0.0001	0.4225
Dyy	0.0011	0.0001	0.0011	0.0001	0.8597
Dzz	0.0005	0.0001	0.0005	0.0001	0.9065
Subcortical fiber
Dxx	0.0011	0.0001	0.0010	0.0001	0.4481
Dyy	0.0007	0.0002	0.0007	0.0001	0.6660
Dzz	0.0006	0.0001	0.0007	0.0002	0.1136
DTI-ALPS index	1.2887	0.1999	1.1834	0.1978	0.3307

CKD, chronic kidney disease; DM, diabetic mellitus; SD, standard deviation; Dxx, diffusivity along the x-axis; Dyy, diffusivity along the y-axis; Dzz, diffusivity along the z-axis; DTI-ALPS index, diffusion tensor image analysis with the perivascular space index; HTN, hypertension.