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. 2022 Aug 8;13:886953. doi: 10.3389/fendo.2022.886953

Table 1.

Clinical characteristics of controls and HT patients.

Character Control (n=866) HT-C (n=393) HT+C (n=44) P-value
Goiter degree <0.0001
None 859 (99.19%) 36 (9.16%) ↓ 1 (2.27%) ↓
I 3 (0.35%) 183 (46.56%) ↑ 13 (29.55%) ↑
II 2 (0.23%) 165 (41.98%) ↑ 29 (65.91%) ↑
III 2 (0.23%) 9 (2.29%) ↑ 1 (2.27%) ↑
Age (years) 54.06 ± 13.50 47.66 ± 13.09 ↓ 51.45 ± 11.86 ↓ <0.0001
BMI (kg/m2) 24.49 ± 3.31 23.15 ± 3.55 ↓ 24.64 ± 3.31 ↑ <0.0001
Gender <0.0001
Male 508 (58. 66%) 49 (12.47%) ↓ 8 (18.18%) ↓
Female 358 (41.34%) 344 (87.53%) ↑ 36 (81.82%) ↑
Diabetes 0.0433
Yes 28 (3.23%) 24 (6.11%) ↑ 3 (6.82%) ↑
No 838 (96.77%) 369 (93.89%) ↓ 41 (93.18%) ↓

The table shows the statistics of clinical characteristics and laboratory results of controls, HT patients and patients with thyroid cancer. There were significant differences in most factors between controls and HT patients. BMI, body mass index. P-values were calculated by Kruskal–Wallis H test or Chi-square test among the triple groups.

Symbols "↓ and ↑" represent “reduced and increased” change in mean values compared to corresponding controls.