TABLE 2.
The ROC curve of left hippocampal structural images, ALFF in slow-5 frequency band and their combined model.
| Classifier | Model | Data set | AUC | 95% CI | Accuracy |
| AD vs. NCs | T1 | Training | 0.864 | 0.841–0.887 | 0.778 |
| Test | 0.818 | 0.767–0.858 | 0.790 | ||
| ALFF | Training | 0.828 | 0.801–0.853 | 0.767 | |
| Test | 0.809 | 0.758–0.856 | 0.816 | ||
| T1+ALFF | Training | 0.873 | 0.849–0.895 | 0.789 | |
| Test | 0.837 | 0.792–0.872 | 0.763 | ||
| aMCI vs. NCs | T1 | Training | 0.729 | 0.689–0.766 | 0.682 |
| Test | 0.713 | 0.650–0.772 | 0.786 | ||
| ALFF | Training | 0.764 | 0.725–0.800 | 0.788 | |
| Test | 0.738 | 0.678–0.796 | 0.714 | ||
| T1+ALFF | Training | 0.804 | 0.763–0.834 | 0.788 | |
| Test | 0.718 | 0.657–0.774 | 0.714 |
AD, Alzheimer’s disease; aMCI, amnestic mild cognitive impairment; NCs, normal controls; ROC, area under the curve; ALFF, the amplitude of low frequency fluctuation.