Table 2.
Clinical Trials currently open evaluating PT for HCC.
| Study Title | Principal Institution | Type of trial | ClinicalTrials.gov Identifier | Estimated Enrollment | Actual Study Start Date | Estimated Study Completion Date |
|---|---|---|---|---|---|---|
| Feasibility of High Dose Proton Therapy On Unresectable Primary Carcinoma Of Liver: Prospective Phase II trial | Samsung Medical Center, Seoul, Korea | Monoinstitutional, Phase II |
NCT02632864 | 66 participants | 2015 | 2022 |
| Proton Beam Therapy in Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis (PTHP) | Samsung Medical Center, Seoul, Korea | Monoinstitutional, Phase II |
NCT02571946 | 53 participants | 2015 | 2022 |
| Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer | NRG Oncology Massachusetts General Hospital Cancer Center, USA |
Multicentric, Phase III |
NCT03186898 | 186 participants | 2017 | 2029 |
| Stereotactic Body Proton Radiotherapy for the Treatment of Liver Cancer | Mayo Clinic, USA | Multicentric, Phase II |
NCT04805788 | 60 participants | 2021 | 2025 |
| A National Phase II Study of Proton Therapy in Hepatocellular Carcinoma | Aarhus University Hospital, Denmark | Multicentric, Phase II |
NCT05203120 | 50 participants | 2022 | 2030 |