Table 3.
Association of age, sex, race, eGFR, and BMI with severe (stage 3) AKI
| Unadjusted OR (95% CI) | Adjusted OR (95% CI) | |
|---|---|---|
| Age (per 10-year ↑) | 1.01 (0.89, 1.15) | 0.80 (0.66, 0.96) |
| Baseline eGFR (per 5 mL/min/1.73 m2 ↑) | 0.92 (0.89, 0.96) | 0.91 (0.87, 0.95) |
| Body mass index (vs. < 25 kg/m2) | ||
| ≥35 kg/m2 | 1.95 (1.11, 3.41) | 2.23 (1.14, 4.38) |
| 30 to <35 kg/m2 | 1.31 (0.76, 2.28) | 1.57 (0.84, 2.95) |
| 25 to <30 kg/m2 | 1.66 (0.98, 2.82) | 1.71 (0.95, 3.09) |
| Male gender (vs. female gender) | 1.92 (1.28, 2.94) | 2.17 (1.37, 3.45) |
| Race (vs. white) | ||
| Black | 2.02 (1.28, 3.18) | 2.22 (1.33, 3.72) |
| Hispanic | 1.25 (0.70, 2.24) | 1.21 (0.63, 2.34) |
| Asian/Native American | 2.41 (1.20, 4.86) | 3.05 (1.41, 6.60) |
| APACHE IV score (per 20-point ↑) | 1.52 (1.30, 1.77) | 1.48 (1.24, 1.76) |
N = 459; Events = 174; models are based on multiple imputation with chained equations to create 20 multiple complete datasets. eGFR, estimated glomerular filtration rate; BMI, body mass index; APACHE, acute physiology and chronic health evaluation; OR, odds ratio; CI, confidence interval.