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. 2022 Apr 13;66(4):279–294. doi: 10.1159/000524260

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Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel

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Fig. 2 — CIC-rearranged sarcoma. a, b Hypercellular smears with tight clusters or dispersed tumor cells showing centrally or eccentrically placed nuclei with coarse chromatin pattern, small nucleoli and poorly preserved cytoplasmic borders creating slender cytoplasmic processes connecting one cell to another (H&E staining). c, d. Small traversing vessels within cell sheets, apoptosis and myxoid stroma presented in smears (H&E staining). e–g Divergent but distinctive findings include desmoplastic matrix, tigroid background, and cells with a rhabdoid morphology (MGG and H&E stains).