TABLE 1.

Histological scoring criteria for cruciate ligament and OARSI

	Parameter
Cruciate ligament scoring	ECM staining
	Cell hypertrophy
	Cell clustering
	Loss of alignment
Cartilage degeneration scoring	Normal articular cartilage, no degeneration (grade 0)
	Loss of Safranin‐O without structural changes (grade 0.5)
	Small fibrillations without loss of cartilage (grade 1)
	Vertical clefts down to the layer immediately below the superficial layer and some loss of surface lamina (grade 2)
	Vertical clefts/erosion to the calcified cartilage extending to <25% of the articular surface (grade 3)
	Vertical clefts/erosion to the calcified cartilage extending to 25–50% of the articular surface (grade 4)
	Vertical clefts/erosion to the calcified cartilage extending to 50–75% of the articular surface (grade 5)
	Vertical clefts/erosion to the calcified cartilage extending >75% of the articular surface (grade 6)