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. 2022 Aug 22;23:350. doi: 10.1186/s12859-022-04894-6

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Identification of prognostic cuproptosis-related genes in breast cancer. A 4 cuproptosis-related genes, DLAT, SLC31A1, ATP7A and ATP7B, were correlated with prognosis of breast cancer patients. B Expression of SLC31A1 in tumor samples was higher than that in normal samples in breast cancer. C For each patient, tumor tissues generally showed higher expression levels of SLC31A1 than normal tissues, based on data from TCGA database. Y-axis represents log2 (TPM) values of SLC31A1 expression of samples. D Pan-cancer expression analysis of SLC31A1 between normal and tumor samples according to TIMER. BLCA, bladder urothelial carcinoma; BRCA, breast invasive carcinoma; CESC, cervical squamous cell carcinoma and endocervical adenocarcinoma; ESCA, esophageal carcinoma; GBM, glioblastoma multiforme; HNSC, head and neck squamous cell carcinoma; PCPG, pheochromocytoma and paraganglioma; STAD, stomach adenocarcinoma; UCEC, uterine corpus endometrial carcinoma; CHOL, cholangiocarcinoma; KIRC, kidney renal clear cell carcinoma; KIRP, kidney renal papillary cell carcinoma; LUSC, lung squamous cell carcinoma; prostate adenocarcinoma; THCA, thyroid carcinoma; *P < 0.05, **P < 0.01, ***P < 0.001