Table 5.
Independent association of vaccination and period of admission with outcomes in COVID-positive patients by age group (predominantly-Delta and -Omicron periods only)
| Outcome | Age group | In vaccinated | In non- vaccinated | p | OR for vaccinated vs. non-vaccinated (95% CI)a | p | OR for omicron vs. delta (95% CI)a | p |
|---|---|---|---|---|---|---|---|---|
| COVID pneumonia in hospitalized COVID-positive patients | < 55 | 138 (40.6%) | 368 (71.7%) | < 0.0001 | 0.27 (0.19–0.38) | < 0.0001 | 0.31 (0.22–0.44) | < 0.0001 |
| 55–65 | 139 (64.1%) | 152 (86.4%) | < 0.0001 | 0.33 (0.19–0.57) | < 0.0001 | 0.37 (0.20–0.68) | 0.0013 | |
| 65–75 | 156 (59.8%) | 126 (80.8%) | < 0.0001 | 0.36 (0.22–0.59) | < 0.0001 | 0.73 (0.46–1.16) | 0.18 | |
| 75–85 | 153 (60.5%) | 85 (77.3%) | 0.0020 | 0.41 (0.24–0.71) | 0.0014 | 1.15 (0.71–1.86) | 0.57 | |
| 85+ | 123 (67.6%) | 50 (80.6%) | 0.0505 | 0.49 (0.23–1.04) | 0.06 | 0.76 (0.39–1.48) | 0.42 | |
| Inpatient mortality in COVID-positive patients | < 55 | 7 (2.1%) | 18 (3.5%) | 0.22 | 0.37 (0.14–1.00) | 0.0496 | 0.36 (0.15–0.88) | 0.0241 |
| 55–65 | 15 (6.9%) | 16 (9.1%) | 0.43 | 0.46 (0.20–1.06) | 0.07 | 0.68 (0.30–1.55) | 0.36 | |
| 65–75 | 31 (11.9%) | 19 (12.2%) | 0.93 | 0.95 (0.50–1.81) | 0.87 | 0.50 (0.27–0.93) | 0.0296 | |
| 75–85 | 27 (10.7%) | 17 (15.5%) | 0.20 | 0.52 (0.25–1.06) | 0.07 | 1.06 (0.51–2.22) | 0.87 | |
| 85+ | 19 (10.4%) | 7 (11.3%) | 0.85 | 0.89 (0.32–2.50) | 0.82 | 2.45 (0.82–7.34) | 0.11 |
aAdjusted for age, sex, Elixhauser’s comorbidity index (ECI), and morbid obesity in a logistic regression model