Table 3.
Association of SARS-CoV-2 VOC variants and age with disease severity, Cuba, December 28, 2020 – September 28, 2021.
| Severity |
Crude prevalence ratio |
Adjusted prevalence ratio |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Characteristic | N | Total N = 1406a | Non-severe N = 1196a | Severe N = 210a | PRb | 95% CIb | p-value | PRb | 95% CIb | p-value |
| VOC | 868 (62%) | 699 (58%) | 169 (80%) | 2.55 | 1.84, 3.64 | <0.001 | 1.96 | 1.34, 2.93 | <0.001 | |
| Age | 1075 | |||||||||
| ≤44 | 542 (50%) | 525 (56%) | 17 (13%) | — | — | — | — | |||
| 45–54 | 177 (16%) | 166 (18%) | 11 (8.5%) | 1.98 | 0.90, 4.18 | 0.077 | 2.08 | 0.95, 4.40 | 0.058 | |
| 55–69 | 197 (18%) | 155 (16%) | 42 (32%) | 6.80 | 3.94, 12.3 | <0.001 | 6.52 | 3.78, 11.8 | <0.001 | |
| ≥70 | 159 (15%) | 99 (10%) | 60 (46%) | 12.0 | 7.19, 21.3 | <0.001 | 11.5 | 6.84, 20.3 | <0.001 | |
| Unknown | 331 | 251 | 80 | |||||||
| Sex | 1361 | |||||||||
| Female | 671 (49%) | 565 (49%) | 106 (51%) | — | — | — | — | |||
| Male | 690 (51%) | 587 (51%) | 103 (49%) | 0.94 | 0.72, 1.24 | 0.7 | 1.14 | 0.81, 1.62 | 0.4 | |
| Unknown | 45 | 44 | 1 | |||||||
a
n (%).
b
PR = Prevalence Ratio, CI = Confidence Interval.