Figure 11.

A. Microscopic pictures of immunostained sections of hippocampal sections against synaptophysin showing many positively brown stained neurons in pyramidal layer in CA3 region in both (A,B) control group and group which received CeNPs. (C) Hippocampal sections from the DOX group show negatively stained neurons. (D) Hippocampal sections from treated group DOX + CeNPs show increased numbers of positively brown stained neurons (yellow arrows). (E) Histogram of % area of immunostaining hippocampal synaptophysin. Values are shown as mean ± SD. One-way ANOVA with Tukey post hoc analysis was conducted. *** p < 0.001, ## p < 0.01. Magnification ×400. Scale bar = 50 µm.