(a) Changes in the average normalized concentration of all carotenoids and lycopene in the SC of the inner forearm in 12 volunteers after irradiation with IR-A and IR-B light (white column) and IR-A light (gray column) in comparison with non-irradiated skin (black column), measured in vivo by RRS using an irradiation dose of 306–342 J/cm2: light intensity 170–190 mW/cm2 and an irradiation time of 30 min. (b) Dependence of the PCA radical marker EPR with shown intensity changes in the SC of non-irradiated porcine ear skin (curve 1), under irradiation of the skin with IR-A light (curve 2), and with IR-A and IR-B light (curve 3). An irradiation dose of 189–207 J/cm2, a light intensity of 105–115 mW/cm2, and an irradiation time of 30 min was applied. “*”, “**”, “***” are statistically significant differences for curves “1” and “2”, “1” and “3”, “2” and “3” (Wilcoxon test, p < 0.05). The figure is adapted from [177].