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. 2022 Jul 24;12(8):975. doi: 10.3390/brainsci12080975

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Pesticide-induced inhibition of mitochondrial complex I and complex III activities. Rats were dosed with malathion (MAL) (A,D); chlorpyrifos (CPF) (B,E); or paraquat (PQ) (C,F); at low, medium, or high dosages and the activity of mitochondrial complex I and complex III enzymes quantified within the hippocampus (HC), corpus striatum (CS), cerebellum (CER), and cerebral cortex (CC). Histograms are representative of mean values with SDs, with significant changes marked with asterisks, according to * p < 0.05, ** p < 0.01, and *** p < 0.001.

Pesticide-induced inhibition of mitochondrial complex I and complex III activities. Rats were dosed with malathion (MAL) (A,D); chlorpyrifos (CPF) (B,E); or paraquat (PQ) (C,F); at low, medium, or high dosages and the activity of mitochondrial complex I and complex III enzymes quantified within the hippocampus (HC), corpus striatum (CS), cerebellum (CER), and cerebral cortex (CC). Histograms are representative of mean values with SDs, with significant changes marked with asterisks, according to * p < 0.05, ** p < 0.01, and *** p < 0.001.