. 2022 Jul 25;12(8):1211. doi: 10.3390/jpm12081211

Table 2.

Association between benign ovarian tumor and ovarian cancer patients. The results of independent sample t-test with blood samples, general biochemistry tests and tumor markers. N.B. BOT: Benign Ovarian Tumor; OC: Ovarian Cancer; SD: Standard Deviation.

Abbreviation	Biomarkers	Type	Unit	Mean ± SD		95% CI	p
Abbreviation	Biomarkers	Type	Unit	BOT	OC	95% CI	p
MPV	Mean platelet volume	full blood	fL	$9.98 \pm 1.78$	$10.09 \pm 1.69$	(−0.48, 0.25)	0.55
BASO#	Basophil cell count	full blood	$10^{9}$ /L	$0.28 \pm 0.02$	$0.03 \pm 0.02$	(−0.006, 0.002)	0.28
PHOS	Phosphorus	serum	mmol/L	$1.12 \pm 0.18$	$1.12 \pm 0.19$	(−0.05, 0.03)	0.67
GLU	Glucose	serum	mmol/L	$5.56 \pm 1.18$	$5.12 \pm 0.85$	(0.18, 0.69)	<0.01
CA72-4	Carbohydrate antigen 72-4	serum	U/mL	$12.77 \pm 19.32$	$7.67 \pm 4.15$	(2.18, 8.01)	<0.01
K	Kalium	serum	mmol/L	$4.38 \pm 0.41$	$4.39 \pm 0.39$	(−0.4, −1.17)	0.92
AST	Aspartate aminotransferase	serum	u/L	$20.94 \pm 9.36$	$17.34 \pm 6.88$	(1.87, 5.32)	<0.01
BASO%	Basophil cell ratio	full blood	%	$0.44 \pm 0.33$	$0.52 \pm 0.36$	(−0.15, −0.001)	0.05
Mg	Magnesium	serum	mmol/L	$0.98 \pm 0.13$	$0.98 \pm 0.12$	(−0.03, 0.02)	0.78
CL	Chlorine	serum	mmol/L	$100.9 \pm 3.52$	$100.73 \pm 2.36$	(−0.05, 1.07)	0.6
CEA	Carcinoembryonic antigen	serum	ng/mL	$5.23 \pm 15.02$	$1.47 \pm 0.88$	(1.55, 5.98)	<0.01
EO#	Eosinophil count	full blood	$10^{9}$ /L	$0.06 \pm 0.06$	$0.07 \pm 0.08$	(−0.03, 0.003)	0.13
CA19-9	Carbohydrate antigen 19-9	serum	U/mL	$66.66 \pm 166.39$	$25.91 \pm 40.36$	(15.48, 66.01)	<0.01
ALB	Albumin	serum	g/L	$38.94 \pm 6.27$	$43.13 \pm 3.92$	(−5.29, −3.1)	<0.01
IBIL	Indirect bilirubin	serum	umol/L	$5.36 \pm 2.51$	$6.54 \pm 3.15$	(−1.77, −0.57)	<0.01
GGT	Gama glutamyl transferase	serum	u/L	$22.79 \pm 17.22$	$19.88 \pm 18.48$	(−0.85, 6.68)	0.13
MCH	Mean corpuscular hemoglobin	full blood	Pg	$28.34 \pm 2.71$	$29.2 \pm 2.36$	(−1.39, −0.32)	<0.01
GLO	Globulin	serum	g/L	$31.07 \pm 5.04$	$29.32 \pm 3.69$	(0.83, 2.68)	<0.01
ALT	Alanine aminotransferase	serum	u/L	$17.96 \pm 11.79$	$18.06 \pm 10.39$	(−2.44, 2.23)	0.93
DBIL	Direct bilirubin	serum	umol/L	$2.9 \pm 1.34$	$3.35 \pm 1.45$	(−0.74, −0.15)	<0.01
RDW	Red blood cell distribution width	full blood	%	$13.68 \pm 2.0$	$13.43 \pm 1.59$	(−0.13, 0.62)	0.2
PDW	Platelet distribution width	full blood	%	$13.91 \pm 3.19$	$14.74 \pm 2.74$	(−1.46, −0.21)	<0.01
CREA	Creatinine	serum	umol/L	$63.35 \pm 12.59$	$65.11 \pm 10.78$	(−4.23, 0.7)	0.16
AFP	Alpha-fetoprotein	serum	ng/mL	$20.41 \pm 135.44$	$2.72 \pm 2.18$	(−2.28, 37.66)	0.08
HGB	Hemoglobin	full blood	g/L	$122.21 \pm 16.71$	$128.34 \pm 13.7$	(−9.35, −2.93)	<0.01
Na	Natrium	serum	mmol/L	$140.91 \pm 3.26$	$140.1 \pm 2.35$	(0.22, 1.42)	<0.01
HE4	Human epididymis protein 4	serum	pmol/L	$324.24 \pm 488.62$	$49.17 \pm 39.07$	(202.8, 347.34)	<0.01
LYM#	Lymphocyte count	full blood	$10^{9}$ /L	$1.41 \pm 0.54$	$1.7 \pm 0.55$	(−0.4, −0.17)	<0.01
CA125	Carbohydrate antigen 125	serum	U/mL	$652.15 \pm 1021.91$	$51.45 \pm 79.79$	(449.57, 751.81)	<0.01
BUN	Blood urea nitrogen	serum	mmol/L	$4.0 \pm 1.42$	$4.02 \pm 1.15$	(−0.28, 0.26)	0.94
LYM%	Lymphocyte ratio	full blood	%	$22.74 \pm 10.05$	$29.27 \pm 9.7$	(−8.61, −4.46)	<0.01
Ca	Calcium	serum	mmol/L	$2.32 \pm 0.42$	$2.46 \pm 0.28$	(−0.21, −0.06)	<0.01
AG	Anion gap	serum	mmol/L	$19.4 \pm 4.6$	$19.24 \pm 4.09$	(−0.75, 1.08)	0.73
MONO#	Mononuclear cell count	full blood	$10^{9}$ /L	$0.39 \pm 0.16$	$0.33 \pm 0.13$	(−0.03, 0.78)	<0.01
PLT	Platelet count	full blood	$10^{9}$ /L	$281.65 \pm 117.44$	$230.25 \pm 57.33$	(32.06, 70,74)	<0.01
NEU	Neutrophil ratio	full blood	%	$70.21 \pm 10.92$	$63.09 \pm 7.5$	(5.16, 9.09)	<0.01
EO%	Eosinophil ratio	full blood	$10^{9}$ /L	$1.0 \pm 0.94$	$1.24 \pm 1.29$	(−0.48, −0.004)	0.05
TP	Total protein	serum	g/L	$69.66 \pm 8.78$	$72.45 \pm 5.07$	(−4.29, −1.29)	<0.01
UA	Uric acid	serum	$μ$ mol/L	$246.25 \pm 78.04$	$241.26 \pm 58.18$	(−9.46, 19.45)	0.5
RBC	Red blood cell count	full blood	$10^{12}$ /L	$4.31 \pm 0.52$	$4.41 \pm 0.41$	(−0.19, 0.005)	0.06
PCT	Thrombocytocrit	full blood	L/L	$0.27 \pm 0.1$	$0.23 \pm 0.07$	(0.02,0.06)	<0.01
CO2CP	Carban dioxide-combining power	serum	mmol/L	$24.54 \pm 2.97$	$24.03 \pm 2.36$	(−0.05, 1.07)	0.08
TBIL	Total bilirubin	serum	$μ$ mol/L	$8.27 \pm 3.6$	$9.88 \pm 4.4$	(−2.46, −0.77)	<0.01
HCT	Hematocrit	full blood	L/L	$0.38 \pm 0.05$	$0.39 \pm 0.04$	(−0.02, −0.002)	0.02
MONO%	Monocyte ratio	full blood	%	$5.77 \pm 2.01$	$5.4 \pm 1.82$	(−0.03, 0.78)	0.07
MCV	Mean corpuscular volume	full blood	fL	$87.79 \pm 6.71$	$88.34 \pm 5.32$	(−1.82, 0.72)	0.4
ALP	Alkaline phosphatase	serum	u/L	$86.56 \pm 57.77$	$67.98 \pm 19.61$	(9.56, 27.59)	<0.01