Table 1.
Summary of clinical features and treatment outcomes for patients with infective endocarditis caused by C. canimorsus reported in the literature based on a PubMed literature search 1977–2021 using the search terms ‘Capnocytophaga Canimorsus Endocarditis.’
|
Case |
Age/sex |
Comorbidities/risk factors |
Source of infection |
Valve involved |
Surgery intervention |
Antibiotic used (duration, days) |
Complications |
Outcome |
Reference |
|---|---|---|---|---|---|---|---|---|---|
|
1 |
50/M |
nd |
Dog bite |
AV |
Yes |
nd |
nd |
Died |
[14] |
|
2 |
nd |
nd |
nd |
AV |
Yes |
Penicillin G |
nd |
Cured |
[14] |
|
3 |
nd |
nd |
nd |
MV |
No |
Penicillin G |
nd |
Cured |
[14] |
|
4 |
64/M |
nd |
Dog bite |
TV, AV |
No |
Vancomycin+gentamicin |
nd |
Died |
[15] |
|
5 |
59/F |
Atrial myxoma, CLL, steroid use |
nd |
TV |
Yes |
Cephalothin+gentamicin (14) |
nd |
Died |
[16] |
|
6 |
39/M |
Alcohol abuse |
Dog contact |
MV |
No |
Ampicillin (42)+tobramycin |
Glomerulonephritis |
Cured |
[17] |
|
7 |
24/M |
Heart murmur |
Dog bite |
AV |
No |
Penicillin (28) |
nd |
Cured |
[18] |
|
8 |
47/M |
Alcohol abuse |
Dog contact |
TV |
Yes |
Vancomycin (14)+gentamicin (14)+penicillin (42) |
nd |
Cured |
[19] |
|
9 |
56/M |
nd |
Dog contact |
TV |
No |
Penicillin (42)+gentamicin (NS) |
nd |
Cured |
[20] |
|
10 |
52/M |
Aortic stenosis, pacemaker |
Dog bite |
AV |
No |
Penicillin G, aztreonam (35) |
nd |
Cured |
[21] |
|
11 |
69/F |
COPD |
None |
TV |
No |
Cefuroxime (7)+gentamicin (7),+flucloxacillin (7), penicillin G (42) |
nd |
Cured |
[22] |
|
12 |
63/M |
Aortic valve replacement |
Dog contact |
PAV |
Yes |
Ceftriaxone (28)+gentamicin (28), penicillin G (28) |
Anaemia, CHF |
Cured |
[23] |
|
13 |
41/F |
Rheumatic mitral valve disease |
Dog contact |
MV |
Yes |
Ceftriaxone |
nd |
Cured |
[24] |
|
14 |
42/M |
Alcohol abuse |
Dog bite |
AV |
Yes |
Ceftriaxone +gentamicin |
nd |
Cured |
[25] |
|
15 |
55/M |
COPD, alcohol abuse, i.v. drug user |
Dog |
AV, TV |
Yes |
Meropenem+ciprofloxacin |
nd |
Cured |
[26] |
|
16 |
65/M |
Dislipidemia, aortic stenosis, hypertension |
None |
AV, TV |
Yes |
Ampicillin +gentamicin |
Anaemia, renal insufficiency |
Cured |
[27] |
|
17 |
73/M |
Prosthetic atrial valve, atrial fibrillation, diabetes, renal insufficiency |
Dog contact |
AV |
No |
Meropenem+ciprofloxacin |
Anaemia |
Cured |
[28] |
|
18 |
43/M |
Alcohol abuse |
Lion bite |
AV, MV |
Yes |
Ceftriaxone+gentamicin+vancomycin |
None |
Died |
[29] |
|
19 |
76/F |
ICD |
Dog scratch |
ICD |
Yes |
nd |
nd |
Cured |
[30] |
|
20 |
49/F |
None |
Dog faeces |
TV |
Yes |
Meropenem (42) |
Pulmonary embolism |
Cured |
[31] |
|
21 |
46/M |
None |
Dog bite |
AV |
|
Gentamicin +cefazolin, ceftriaxone (28) |
nd |
Cured |
[9] |
|
22 |
59/F |
None |
Dog contact |
AV |
Yes |
Meropenem+vancomycin+gentamicin, i.v. benzylpenicillin (28) |
nd |
Cured |
[32] |
|
23 |
47/M |
None |
Dog contact |
AV |
Yes |
Meropenem (42) |
nd |
Cured |
[33] |
|
24 |
70/F |
Osteoarthritis, heart murmur, thymoma |
Dog contact |
TV |
Yes |
Benzylpenicillin (14) |
Pulmonary embolism |
Cured |
[34] |
|
25 |
63/M |
ESRD on HD, COPD, nephrectomy, prostate/lung cancer |
Dog contact |
TV |
No |
Piperacillin/tazobactam, amoxicillin/clavulanate, ceftriaxone +gentamicin |
nd |
Cured |
[35] |
M, male; F, female; nd, not documented, AV, aortic valve; MV, mitral valve; TV, tricuspid valve; ICD, implantable cardioverter defibrillator; COPD, chronic obstructive pulmonary disease; ESRD, end stage renal disease; HD, hemodialysis; T2DM, type 2 diabetes mellitus, CLL, chronic lymphocytic leukaemia.