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Various types of drugs for osteoarthritis can be loaded in NPs and then introduced into the articular cavity. The specific conjugates assembled with OA targets can mediate the action of NPs to a specific location, thus achieving accurate localization. Nanoscale cladding with the property of evading scavenging allows the drug to act longer. When the carrier has the characteristics of temperature sensitivity or PH sensitivity, the drug can have adjustable release characteristics.
