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. 2022 Aug 18;15:4627–4636. doi: 10.2147/IDR.S371285

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© 2022 Jiang et al.

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Isolation of CZA-resistant Klebsiella pneumoniae and detection of the enzyme type of the strain. (A) The top panel shows that CZA-resistant Klebsiella pneumonia was isolated from the puncture fluid sample of patient 1 after 10 days of CZA administration, and the sensitivity of CZA, MEM, and IMP was tested by the K-B method. The bottom panel in (A) and (B) shows that the enzyme types of isolates LY0F1-1, LY0F1-2 and HM0F1 were detected by enzyme inhibitor enhancement experiments and mCIM and eCIM experiments.

Abbreviations: MEM, meropenem; TGC, tigecycline; CZA, ceftazidime/avibactam; mCIM, modified carbapenem inactivation method; eCIM, EDTA-modified carbapenem inactivation method.